331440-04-1Relevant articles and documents
Metal-free transamidation of benzoylpyrrolidin-2-one and amines under aqueous conditions
Joseph, Devaneyan,Lee, Sunwoo,Park, Myeong Seong
supporting information, p. 6227 - 6232 (2021/07/28)
N-Acyl lactam amides, such as benzoylpyrrolidin-2-one, benzoylpiperidin-2-one, and benzoylazepan-2-one reacted with amines in the presence of DTBP and TBAI to afford the transamidated products in good yields. The reactions were conducted under aqueous conditions and good functional group tolerance was achieved. Both aliphatic and aromatic primary amines displayed good activity under metal-free conditions. A radical reaction pathway is proposed.
Nickel/Briphos-Catalyzed Direct Transamidation of Unactivated Secondary Amides Using Trimethylsilyl Chloride
Yu, Subeen,Shin, Taeil,Zhang, Maosheng,Xia, Yuanzhi,Kim, Hyunwoo,Lee, Sunwoo
supporting information, p. 7563 - 7566 (2019/01/03)
Direct transamidation of secondary amides was developed via nickel catalysis. In the presence of trimethylsilyl chloride and manganese, Ni(diglyme)Cl2 with a Briphos ligand efficiently promoted the transamidation of N-aryl benzamide derivatives with primary amines to afford the corresponding secondary amides in moderate to good yields. Primary amines bearing electron-donating groups gave higher yields of the transamidation products.
The First ZnII-Catalyzed Oxidative Amidation of Benzyl Alcohols with Amines under Solvent-Free Conditions
Wu, Xiao-Feng,Sharif, Muhammad,Pews-Davtyan, Anahit,Langer, Peter,Ayub, Khurshid,Beller, Matthias
supporting information, p. 2783 - 2787 (2013/06/26)
The first zinc-catalyzed oxidative amidation of benzyl alcohols has been developed. Both aliphatic and aromatic amines can be tolerated and applied in this reaction. Various amides were prepared in good yields under solvent-free and mild conditions. Copyright
