331456-63-4

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 20452-28-2 phenyl 1-thio-β-D-xylopyranoside 
• 331456-61-2 Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside 
• 331456-62-3 2,3,4-Tris-O-(tert-butyldimethylsilyl)-β-D-xylopyranosyl phenyl sulfone 

Downstream Products

• 54336-64-0 (2S,3R,4E)-2-(N-stearoylamino)-4-octadecene-1,3-diol 
• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 
• 103348-49-8 2-azido-sphingosine 
• 114275-40-0 (2R,3R)-trans-2-azide-1,3-O-benzylidene-1,3-octadec-4-enediol 
• 114275-39-7 (2R,3R,4E)-1,3-benzylidene-4-octadecene-1,2,3-triol 

Relevant academic research and scientific papers

Synthesis of D-erythro-sphingosine and D-erythro-ceramide.

A 1,2-metallate rearrangment of a higher order cuprate derived from an alpha-lithiated xylal derivative and tridecyllithium is the key step in a synthesis of D-erythro-sphingosine and ceramide. A convenient method for preparing alpha-lithiated glycals from alpha-phenylsulfinyl glycals is also described.

The preparation of 1-tributylstannyl glycals from 1-phenylsulfonyl glycals via Ni(0)-catalysed coupling with tributylstannylmagnesium bromide

1-Phenylsulfonyl glycals undergo an easy Ni(0)-catalysed coupling with tributylstannylmagnesium bromide to give the corresponding 1-tributylstannyl glycals in good yield.