33157-76-5

Upstream product

• 5022-29-7 N-ethylphthalimide 
• 100-39-0 benzyl bromide 

Downstream Products

• 40523-37-3 2-ethyl-3-benzylidene-isoindolin-1-one 
• 40523-38-4 2-ethyl-3-((Z)-benzylidene)-isoindolin-1-one 
• 32003-14-8 4-benzyl-2H-phthalazin-1-one 

Relevant academic research and scientific papers

Synthesis of 4-Alkyl-1(2H)-phthalazinones and 4-Alkyl-2, 3-benzoxazin-1-ones via Ring Cleavage of 3-Substituted N-Alkylated-3-hydroxyisoindolin-1-ones

N-Alkyl (Me, Et, i-Pr, t-Bu)-substituted phthalimdes 5a-d were easily transformed to 1(2H)-phthalazinones 8d-i and 2,3-benzoxazin-1-ones 9d, f, and j via a one-pot addition-decyclization-cyclocondensation process.