331652-57-4 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
The chemical structure describes the arrangement of atoms and the type of chemical bonds that hold them together in the compound.
Explanation
The compound's ability to provide health benefits or treat specific medical conditions, making it a valuable component in the synthesis of pharmaceutical compounds.
Explanation
The compound's role in the creation of different drugs, highlighting its significance in the pharmaceutical industry.
Explanation
The compound's potential for further study and development to create new medications or improve existing ones, emphasizing its importance in the field.
Chemical Structure
Piperazine derivative with a chloro-nitrophenyl group and a methyl group attached to the piperazine ring.
Application
Medicine and pharmaceuticals
Therapeutic Properties
Potential as an active ingredient in certain medications
Importance
Valuable component in the synthesis of various pharmaceutical compounds
Research and Development
Target for research and development in the pharmaceutical industry
Check Digit Verification of cas no
The CAS Registry Mumber 331652-57-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,1,6,5 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 331652-57:
(8*3)+(7*3)+(6*1)+(5*6)+(4*5)+(3*2)+(2*5)+(1*7)=124
124 % 10 = 4
So 331652-57-4 is a valid CAS Registry Number.
331652-57-4Relevant academic research and scientific papers
5-piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists
Liu, Kevin G.,Robichaud, Albert J.,Bernotas, Ronald C.,Yan, Yinfa,Lo, Jennifer R.,Zhang, Mei-Yi,Hughes, Zoe A.,Huselton, Christine,Zhang, Guo Ming,Zhang, Jean Y.,Kowal, Dianne M.,Smith, Deborah L.,Schechter, Lee E.,Comery, Thomas A.
scheme or table, p. 7639 - 7646 (2011/02/21)
As part of our efforts to develop agents for CNS diseases, we have been focused on the 5-HT6 receptor in order to identify potent and selective ligands for cognitive enhancement. Herein we report the identification of a novel series of 5-piperazinyl-3-sulfonylindazoles as potent and selective 5-HT6 antagonists. The synthesis, SAR, and pharmacokinetic and pharmacological activities of some of the compounds including 3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole (WAY-255315 or SAM-315) will be described.
Specific features of nucleophilic substitution in 1-chloro-3,4- dinitrobenzene
Zotova,Kushakova,Kuznetsov,Rodin,Garabadzhiu
, p. 1473 - 1476 (2007/10/03)
Effects of the solvent, temperature, and nucleophile nature on the selectivity of nucleophilic substitution in 1-chloro-3,4-dinitrobenzene were studied, and optimal conditions were found for the synthesis and isolation of particular products.
Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands
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Page/Page column 17-18, (2008/06/13)
The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor.
