33172-56-4

Usage

Uses

Used in Pharmaceutical Industry:
5-BROMO-2-HYDROXY-3-METHYL-BENZALDEHYDE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex molecular structures required for drug development.
Used in Chemical Industry:
5-BROMO-2-HYDROXY-3-METHYL-BENZALDEHYDE is used as a key component in the production of organic compounds, facilitating the creation of a wide range of chemical products with diverse applications.

Upstream product

• 100-97-0 hexamethylenetetramine 
• 2362-12-1 4-Bromo-2-methylphenol 
• 95-48-7 ortho-cresol 
• 578-58-5 2-methylmethoxybenzene 
• 14804-31-0 2-methyl-4-bromoanisole 
• 50-00-0 formaldehyd 
• 824-42-0 2-methoxy-3-methylbenzaldehyde 

Downstream Products

• 1000415-03-1 N-(5-bromo-3-methylsalicylidene)-4-[bis(5-methyl-2-furyl)methyl]aniline 
• 1000415-02-0 N-(5-bromo-3-methylsalicylidene)-2-[bis(5-methyl-2-furyl)methyl]aniline 
• 1000414-98-1 N-(5-bromo-3-methylsalicylidene)-3-[bis(5-methyl-2-furyl)methyl]aniline 
• 5548-30-1 2,5-dimethoxy-3-methylbenzaldehyde 
• 886503-93-1 5-methoxy-3-methylsalicylaldehyde 
• 913191-20-5 5-bromo-2-hydroxy-3-methylbenzonitrile 

Relevant academic research and scientific papers

Vanadyl salen complexes covalently anchored to an imidazolium ion as catalysts for the cyanosilylation of aldehydes in ionic liquids

Two vanadyl salen complexes having peripheral styryl substituents have been reacted with 1-methyl-3-(3-mercaptopropyl)-imidazolium chloride using azoisobutyronitrile as radical initiator. The resulting compounds contain at the same time a vanadyl salen co

HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Disclosed in the present invention are a heterocyclic compound, an application thereof and a pharmaceutical composition comprising the same. Provided by the present invention are a heterocyclic compound represented by formula I or a pharmaceutically acceptable salt thereof. The compound has a novel structure and a good inhibitory activity against autotaxin (ATX).

Ti-Catalyzed Synthesis of Exocyclic Allenes on Oxygen Heterocycles

A general method for the straightforward synthesis of exocyclic allenes on five-, six-, seven-, and eight-membered oxygen heterocycles is described. A Barbier-type titanocene(III)-catalyzed cyclization of propargyl halides with a pendant carbonyl group is

As the NS4B inhibitor benzofuran analogs (by machine translation)

The present invention discloses a kind of as NS4B benzofuran analogue inhibitors, in particular to the formula (I) below or a pharmaceutically acceptable salt thereof. (by machine translation)

A simple route to polysubstituted indoles exploiting azide induced furan ring opening

A straightforward, efficient indole synthesis based on thermolysis of 2-(2-azidobenzyl)furans with attack of the formed nitrene moiety onto the ipso position of furan ring has been developed. The cyclization is accompanied by furan ring opening and affords indoles with a 2-acylvinyl substituent suitable for further modifications.

Synthesis of deuterated benzopyran derivatives as selective COX-2 inhibitors with improved pharmacokinetic properties

We designed a series of specifically deuterated benzopyran analogues as new COX-2 inhibitors with the aim of improving their pharmacokinetic properties. As expected, the deuterated compounds retained potency and selectivity for COX-2. The new molecules possess improved pharmacokinetic profiles in rats compared to their nondeuterated congeners. Most importantly, the new compounds showed pharmacodynamic efficacy in several murine models of inflammation and pain. The benzopyran derivatives were separated into their enantiomers, and the activity was found to reside with the S-isomers. To streamline the synthesis of the desired S-isomers, an organocatalytic asymmetric domino oxa-Michael/aldol condensation reaction was developed for their preparation.

PAI-1 INHIBITOR

The compound represented by the following formula (I) and the like have PAI-1 inhibition activity; wherein: R1 represents a C6-10 aryl group which may be substituted or the like; T represents a single bond or the like; m represents 0

Vanadyl salen complexes covalently anchored to single-wall carbon nanotubes as heterogeneous catalysts for the cyanosilylation of aldehydes

Single-wall carbon nanotubes (SWNT) have a special structure and morphology consisting of long tubes (μm scale) of less than 2 nm in diameter. We have taken advantage of this geometric feature of SWNT to use them as supports for the preparation of a heter

BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (1). Wherein Z, X, R1, R2, R3, and R4 are as described in specification.

CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (I). Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.