331728-62-2

Upstream product

• 331729-12-5 2-cyano-4-chlorophenoxyacetic acid tert-butyl ester 
• 331729-03-4 (2S,3S,4R,5R)-3-azido-5-(6-chloro-purin-9-yl)-4-acetoxy-tetrahydro-furan-2-carboxylic acid methylamide 
• 331729-04-5 3-azido-3-deoxy-1,2-diacetoxy-α-D-ribofuranuronic acid methyl amide 
• 331729-05-6 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranuronic acid methyl amide 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 86945-40-6 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranuronic acid 
• 13589-72-5 5-chloro-2-hydroxybenzonitrile 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 55951-93-4 1,2:5,6-di-O-isopropylidene-3-O-triflyl-α-D-glucofuranose 
• 21870-78-0 3-azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 35085-26-8 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose aldehyde 
• 331728-87-1 2-aminomethyl-4-chlorophenoxyacetic acid tert-butyl ester 
• 331728-86-0 (2S,3S,4R,5R)-3-azido-5-(6-chloro-purin-9-yl)-4-hydroxy-tetrahydro-furan-2-carboxylic acid methylamide 

Downstream Products

• 331728-58-6 (2S,3S,4R,5R)3-azido-5-{6-[5-chloro-2-(2-oxo-2-piperazin-1-yl-ethoxy)-benzylamino]-purin-9-yl}-4-hydroxy-tetrahydro-furan-2-carboxylic acid methylamide 
• 331728-61-1 (2R,3R,4S,5S)(2-{[9-(4-azido-3-hydroxy-5-methylcarbamoyl-tetrahydrofuran-2-yl)-9H-purin-6-ylamino]-methyl}-4-chlorophenoxy)acetic acid 

Relevant academic research and scientific papers

The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor

Using a combination of parallel and directed synthesis, the discovery of a highly potent and selective series of adenosine A3 agonists was achieved. High aqueous solubility, required for the intended parenteral route of administration, was achi

Compounds for the treatment of ischemia

A3 agonists, methods of using such A3 agonists and pharmaceutical compositions containing such A3 agonists. The A3 agonists are useful for the reduction of tissue damage resulting from tissue ischemia or hypoxia