331746-63-5Relevant articles and documents
Discovery of tertiary aminoacids as dual PPARα/γ agonists-I
Devasthale, Pratik V.,Chen, Sean,Jeon, Yoon,Qu, Fucheng,Ryono, Denis E.,Wang, Wei,Zhang, Hao,Cheng, Lin,Farrelly, Dennis,Golla, Rajasree,Grover, Gary,Ma, Zhengping,Moore, Lisa,Seethala, Ramakrishna,Sun, Wei,Doweyko, Arthur M.,Chandrasena, Gamini,Sleph, Paul,Hariharan, Narayanan,Cheng, Peter T.W.
, p. 2312 - 2316 (2008/02/01)
A novel series of potent dual agonists of PPARα and PPARγ, the alkoxybenzylglycines, was identified and explored using a solution-phase library approach. The synthesis and structure-activity relationships of this series of dual PPARα/γ agonists are descri
