227029-27-8

Basic information

• Product Name: 2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHYL METHANESULFONATE
• Synonyms: 2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHYL METHANESULFONATE;2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL METHANESULFONATE;4-Oxazoleethanol, 5-Methyl-2-phenyl-, 4-Methanesulfonate;2-(5-methyl-2-phenyloxazol-4-yl)ethyl methanesulfonate;Methanesulfonic acid 2-(5-methyl-2-phenyloxazol-4-yl)ethyl ester
• CAS NO: 227029-27-8
• Molecular Formula: C₁₃H₁₅NO₄S
• Molecular Weight: 281.33
• Mol File: 227029-27-8.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 490.381°C at 760 mmHg
• Flash Point: 250.373°C
• Appearance: /
• Density: 1.257g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.546
• PKA: 0.96±0.26(Predicted)
• CAS DataBase Reference: 2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHYL METHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHYL METHANESULFONATE(227029-27-8)
• EPA Substance Registry System: 2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHYL METHANESULFONATE(227029-27-8)

Safety Data

• Hazardous Substances Data: 227029-27-8(Hazardous Substances Data)

Usage

General Description

2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethyl methanesulfonate is a chemical compound that is used as a reagent in organic synthesis. It is a derivative of 1,3-oxazoles, which are five-membered heterocyclic compounds containing one oxygen and one nitrogen atom. The compound is commonly used as a protecting group for alcohols in organic synthesis, allowing selective deprotection under specific reaction conditions. It is also utilized as a precursor in the synthesis of various pharmaceuticals and other organic compounds. The methanesulfonate group serves as a leaving group in organic reactions, facilitating the formation of new carbon-carbon or carbon-heteroatom bonds.

InChI:InChI=1/C13H15NO4S/c1-10-12(8-9-17-19(2,15)16)14-13(18-10)11-6-4-3-5-7-11/h3-7H,8-9H2,1-2H3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 103788-65-4 (5-methyl-2-phenyloxazol-4-yl)ethanol 
• 103788-64-3 methyl 2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)acetate 
• 17944-68-2 2-(4-methyl-2-phenyl-1,3-oxazol-5-yl)ethanol 
• 114564-74-8 ethyl (4-methyl-2-phenyl-1,3-oxazol-5-yl)acetate 
• 100718-97-6 ethyl 4-(benzoylamino)-3-oxopentanoate 
• 2198-64-3 N-Benzoylalanine 
• 98-88-4 benzoyl chloride 
• 100-52-7 benzaldehyde 
• 524959-64-6 2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)acetonitrile 
• 107367-98-6 2-(5-Methyl-2-phenyl-4-oxazolyl)-acetic acid 
• 103788-61-0 (5-methyl-2-phenyl-4-oxazolyl)methyl chloride 
• 27492-46-2 4,5-dimethyl-2-phenyl-oxazole 3-oxide 

Downstream Products

• 888707-86-6 C₂₆H₃₀N₂O₅ 
• 1394014-15-3 C₂₆H₂₈N₂O₅ 
• 1394014-16-4 C₂₆H₂₈N₂O₅ 
• 475480-88-7 4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophene-7-carbaldehyde 
• 590411-72-6 methyl 3-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethyloxy]-3-(naphthalen-2-yl)phenyl}propionate 
• 696662-76-7 2-ethoxy-1-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}-3-ethoxypentane 
• 696662-75-6 2-ethoxy-1-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}-3-hydroxypentane 

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