331747-59-2

Upstream product

• 331747-65-0 (2S,3S)-N-tert-butyloxycarbonyl-3-methylpyroglutamic acid 
• 81658-27-7 (S)-tert-butyl 2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 5707-04-0 Phenylselenyl chloride 
• 331747-58-1 t-butyl (2S,3S)-1-t-butoxycarbonyl-3-methylpyroglutamate 
• 331747-64-9 (4S,5S)-N-tert-butyloxycarbonyl-5-hydroxymethyl-4-methylpyrrolidin-2-one 
• 149053-03-2 (4S,5S)-1-t-butoxycarbonyl-5-t-butyldimethylsiloxymethyl-4-methyl-2-pyrrolidone 

Relevant academic research and scientific papers

Synthesis of L-[4,5,5,5-D4]isoleucine: Determination of approximate rotamer population about the Cβ-Cγ bond

An asymmetric synthesis of regio- and stereoselectively deuteriumlabelled L-isoleucine was examined. An unsaturated γ-lactam readily available from L-pyroglutamic acid was stereoselectively methylated by the Gilman reagent and subsequent oxidation of the