331754-75-7

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 146397-87-7 p-(trifluoromethyl)phenyl trifluoromethanesulfonate 
• 402-45-9 4-hydroxybenzotrifluoride 
• 455-13-0 4-Iodobenzotrifluoride 

Relevant academic research and scientific papers

SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION

The present invention relates to catalyst complexes comprising palladium (Pd) and at least one spiro-1,1 '-biindane-7,7'- bisphosphine oxide ligand as disclosed herein, and their use. The present invention is further directed to the asymmetric Pd-catalyzed covalent carbon-carbon single bond formation from aryl, heteroaryl and alkenyl triflates and halides and olefins utilising the said catalyst complexes.

Highly active catalysts of bisphosphine oxides for asymmetric Heck reaction

Bisphosphine oxides formed highly active asymmetric Heck catalysts, which were applied in asymmetric synthesis of pharmacologically active azacycles. Olefin insertion proceeded via cis pathways, different from P,N-ligands.