33176-41-9

Basic information

• Product Name: 2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid
• Synonyms: 2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid;(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid;5-thiazolidineacetic acid, 2-imino-4-oxo-;5-Thiazoleacetic acid,2-aMino-4,5-dihydro-4-oxo-;2-(2-amino-4-keto-thiazol-5-yl)acetic acid;2-(2-amino-4-oxo-1,3-thiazol-5-yl)ethanoic acid;2-(2-amino-4-oxo-5-thiazolyl)acetic acid;2-(2-amino-4-oxo-thiazol-5-yl)acetic acid
• CAS NO: 33176-41-9
• Molecular Formula: C₅H₆N₂O₃S
• Molecular Weight: 174.18
• Mol File: 33176-41-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 235-237 °C
• Boiling Point: 438.1°Cat760mmHg
• Flash Point: 218.7°C
• Appearance: /
• Density: 1.88g/cm³
• Vapor Pressure: 6.71E-09mmHg at 25°C
• Refractive Index: 1.77
• PKA: 3.81±0.10(Predicted)
• CAS DataBase Reference: 2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid(33176-41-9)
• EPA Substance Registry System: 2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid(33176-41-9)

Safety Data

• Hazardous Substances Data: 33176-41-9(Hazardous Substances Data)

Usage

General Description

2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid, also known as Azetidine 2-Carboxylic acid, is a chemical compound with the molecular formula C6H7N3O3S. It is a thiazole derivative containing an amino group and a carboxylic acid group. 2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetic acid is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and drug intermediates. It has also been investigated for its potential biological activities and therapeutic applications due to its unique structural features. Additionally, it has shown potential as an inhibitor of certain enzymes, making it a promising candidate for further research and development.

InChI:InChI=1/C5H6N2O3S/c6-5-7-4(10)2(11-5)1-3(8)9/h2H,1H2,(H,8,9)(H2,6,7,10)

Upstream product

• 420-04-2 CYANAMID 
• 108-31-6 maleic anhydride 
• 17356-08-0 thiourea 
• 2756-87-8 methyl hydrogen fumarate 
• 104445-54-7 (5-Bromo-2-imino-4-oxo-thiazolidin-5-yl)-acetic acid 
• 3052-50-4 monomethyl maleate 
• 110-17-8 (2E)-but-2-enedioic acid 
• 110-16-7 maleic acid 
• 923-06-8 bromosuccinic acid 
• 82745-20-8 methyl hydrogen fumarate sodium salt 

Downstream Products

• 875-97-8 2-(2,4-dioxothiazolidin-5-yl)acetic acid 
• 1163681-09-1 NSC 723448 
• 1163681-08-0 2-amino-5-[(3-benzyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)methyl]-1,3-thiazol-4-ol 
• 5138-18-1 sulfosuccinic acid 
• 57-13-6 urea 

Relevant articles and documents

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Synthesis and antihyperglycemic evaluation of new 2,4-thiazolidinediones having biodynamic aryl sulfonylurea moieties

New 2,4-thiazolidinediones with aryl sulfonylurea moieties 8a-h have been synthesized by condensing various substituted sulfonamides and 5-(isocyanatomethyl) thiazolidino-2,4-dione 6. The isocyanomethyl thiazolidinedione was obtained by using the Curtius

The Reaction of Thiourea Derivatives with Maleic Acid Anhydride

The reaction of thiourea derivatives with maleic and bromomaleic acid anhydride is described, the chemical structure of the compound obtained is proved; some biologically active acids yield amide derivatives 24-32.Amides of the 1,3-thiazine-6-carboxylic a