331761-34-3

Upstream product

• 5718-83-2 rhodanine 3-acetic acid 
• 623-27-8 terephthalaldehyde, 

Downstream Products

• 1448801-33-9 2-((Z)-5-(4-((E)-(2-(4-chlorobenzoyl)hydrazono)methyl)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid 
• 1448801-35-1 2-((Z)-5-(4-((E)-(2-(1-naphthoyl)hydrazono)methyl)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid 
• 1448801-36-2 2-((Z)-5-(4-((E)-(2-(4-bromobenzoyl)hydrazono)methyl)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid 
• 1448801-37-3 2-((Z)-5-(4-((E)-(2-(4-chlorobenzoyl)hydrazono)methyl)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid 

Relevant academic research and scientific papers

Novel arylhydrazone derivatives bearing a rhodanine moiety: Synthesis and evaluation of their antibacterial activities

A series of arylhydrazone derivatives bearing a rhodanine moiety have been synthesized, characterized, and evaluated as antibacterial agents. Some of these compounds showed potent antibacterial activities against several different strains of Gram-positive bacteria, including multidrug-resistant clinical isolates. Of the compounds tested, IIk and IIIk were identified as the most effective, with minimum inhibitory concentration values of 2-4 μg/mL against multidrug-resistant Gram-positive organisms, including methicillin-resistant and quinolone-resistant Staphylococcus aureus. None of the compounds exhibited any activity against the Gram-negative bacteria Escherichia coli 1356 at 64 μg/mL.