33183-35-6Relevant academic research and scientific papers
Linear Hydroaminoalkylation Products from Alkyl-Substituted Alkenes
Warsitz, Michael,Doye, Sven
supporting information, p. 15121 - 15125 (2020/10/23)
The regioselective conversion of alkyl-substituted alkenes into linear hydroaminoalkylation products represents a strongly desirable synthetic transformation. In particular, such conversions of N-methylamine derivatives are of great scientific interest, because they would give direct access to important amines with unbranched alkyl chains. Herein, we present a new one-pot procedure that includes an initial alkene hydroaminoalkylation with an α-silylated amine substrate and a subsequent protodesilylation reaction that delivers linear hydroaminoalkylation products with high selectivity from simple alkyl-substituted alkenes. For that purpose, new titanium catalysts have been developed, which are able to activate the α-C?H bond of more challenging α-silylated amine substrates. In addition, a direct relationship between the ligand structure of the new catalysts and the obtained regioselectivity is described.
Design, synthesis, and photodegradation of silicon-containing polyureas
Hwu, Jih Ru,King, Ke Yung
, p. 3805 - 3815 (2007/10/03)
Novel N-phenyl aromatic polyureas containing bis[(N,N′- diphenylureylene)methyl]silane units in the skeleton were designed as a new type of photodegradable polymer. These materials were successfully prepared in 88-93% yields by copolymerization of bis(ani
Design and synthesis of new hypocholesterolemic organosilanes with antioxidant properties
Gotteland,Delhon,Junquero,Oms,Halazy
, p. 533 - 538 (2007/10/03)
(Arylamino)methylsilane derivatives 3 have been prepared and identified as potent inhibitors of human LDL oxidation mediated by copper(II). Combination of this property with the structural requirement of squalene epoxidase inhibitors led to the design and synthesis of the (arylamino)methylsilane derivative 4 which was characterised as the first potent, orally active squalene epoxidase inhibitor with antioxidant properties.
