331950-83-5Relevant academic research and scientific papers
Chemical modification of plant alkaloids. III. X-ray diffraction and NMR studies of the structure of 1,3-dimethyl-5-arylmethyl-5-cytisylmethylbarbituric acids
Krasnov,Kartsev,Gorovoi,Khrustalev
, p. 450 - 457 (2002)
The three-dimensional structure of 1,3-dimethyl-5-(4-allyloxybenzyl)-5-cytisylmethylbarbituric acid was found by x-ray structure analysis. A conformation with proximal cytisine and 2,4,6-trioxopyrimidine moieties was observed. Analogous structures for other synthesized 1,3-dimethyl-5-arylmethyl-5-cytisylmethylbarbituric acids and their 2-thio analogs were proved and the intramolecular effects caused by mutual magnetic shielding of spatially proximal groups were studied using PMR.
