332-69-4

Basic information

• Product Name: Bromamide
• Synonyms: Bromamide;3-(4-bromoanilino)-N,N-dimethylpropanamide;3-(4-bromoanilino)-N,N-dimethyl-propionamide;3-[(4-bromophenyl)amino]-N,N-dimethyl-propanamide
• CAS NO: 332-69-4
• Molecular Formula: C₁₁H₁₅BrN₂O
• Molecular Weight: 271.156
• Mol File: 332-69-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 115.5°C
• Boiling Point: 398.1°Cat760mmHg
• Flash Point: 194.6°C
• Appearance: /
• Density: 1.4335 (rough estimate)
• Vapor Pressure: 1.51E-06mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• CAS DataBase Reference: Bromamide(CAS DataBase Reference)
• NIST Chemistry Reference: Bromamide(332-69-4)
• EPA Substance Registry System: Bromamide(332-69-4)

Safety Data

• Hazardous Substances Data: 332-69-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H15BrN2O/c1-14(2)11(15)7-8-13-10-5-3-9(12)4-6-10/h3-6,13H,7-8H2,1-2H3

Upstream product

• 2680-03-7 N,N-Dimethylacrylamide 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 106-40-1 4-bromo-aniline 

Relevant articles and documents

Method for catalyzing amino protection by imidazole hydrochloride

The invention provides an amino protection method which realizes multi-substituted amino protection by using imidazole hydrochloric acid as an accelerator to push derivatives of primary amine, secondary amine and acrylamide to perform Michael addition at a relatively low temperature, wherein the imidazole hydrochloric acid promotes a carbon-nitrogen bond to crack back to the derivatives of primaryamine and acrylamide at a high temperature. The method provided by the invention is simple and economical, high in practicability, free of any other catalysts or additives, capable of protecting amino to have good functional group tolerance and excellent yield and purity, short in reaction time, free from harsh reaction conditions and suitable for industrial production.