33204-48-7

Usage

Uses

Used in Food Industry:
Butanal, 2-methyl-, (2R)is used as a flavoring agent for enhancing the aroma and taste of various food products. Its natural presence in fruits and essential oils contributes to the characteristic flavor of these products.
Used in Cosmetic Industry:
Butanal, 2-methyl-, (2R)is used as a fragrance ingredient in the cosmetic industry. Its unique scent is utilized in creating various perfumes, colognes, and other scented products.
Used in Pharmaceutical Industry:
Butanal, 2-methyl-, (2R)is used in the manufacture of pharmaceutical products, particularly in the development of drugs that require its specific chemical properties. Its presence in essential oils also makes it a potential candidate for medicinal applications.

Upstream product

• 106-98-9 1-butylene 
• 201230-82-2 carbon monoxide 
• 590-18-1 (Z)-2-Butene 
• 116-53-0 (-)-2-methylbutyric acid 
• 137-32-6 (-)-2-Methylbutan-1-ol 

Downstream Products

• 85269-25-6 (-)-betaenone C 
• 85269-23-4 betaenone B 
• 127718-22-3 C₃₉H₅₂O₄ 
• 1501971-58-9 (4R)-4-benzyl-3-((2R,3S,4R)-3-hydroxy-2,4-dimethylhexanoyl)oxazolidin-2-one 
• 1501971-59-0 (2R,3S,4R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2,4-dimethyl-1-oxohexan-3-yl-4-methylbenzenesulfonate 
• 1094390-39-2 pre-tenellin B 
• 1309567-82-5 3-((R,2E,4E,6E,8E)-8,10-dimethyldodeca-2,4,6,8-tetraenoyl)-4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)pyridin-2(1H)-one 
• 1309567-81-4 3-((R,2E,4E,6E)-6,8-dimethyldeca-2,4,6-trienoyl)-4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl)pyridin-2(1H)-one 
• 1309567-80-3 3-((R,2E,4E)-4,6-dimethylocta-2,4-dienoyl)-4-methoxy-5-(4-((4-methoxybenzyl)oxy)phenyl) pyridin-2(1H)-one 
• 66050-75-7 (2'R)-2'-methylbutyl (2R)-α-methoxy-α-(trifluoromethyl)phenylacetate 
• 494844-48-3 (2R,4S,5R,6R)-1-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-2,4,6-trimethyl-octan-3-one 
• 686718-85-4 (E)-(3R,7S,9R)-10-(tert-butyldiphenylsiloxy)-3,5,7,9-tetramethyl-4-decene 

Relevant academic research and scientific papers

High iso Aldehyde Selectivity in the Hydroformylation of Short-Chain Alkenes

The hydroformylation of propene to give predominantly iso-butanal has been achieved; class-leading selectivity is possible even at higher temperatures that deliver fast conversion. Racemic rhodium complexes of bidentate phospholane phosphites derived from tropos-biphenols and unusual solvent systems are the key to the selectivity observed.

Solvent-free asymmetric olefin hydroformylation catalyzed by highly cross-linked polystyrene-supported (R,S)-BINAPHOS-Rh(I) complex

Using an (R,S)-BINAPHOS-Rh(I) catalyst that is covalently anchored to a highly cross-linked polystyrene support, asymmetric hydroformylation of olefins was performed in the absence of organic solvents. The reaction of cis-2-butene, a gaseous substrate, provided (S)-2-methylbutanal with 100% regioselectivity and 82% ee upon treatment with H2 (12 atm) and CO (12 atm) in a batchwise reactor equipped with a fixed bed. The polymer-supported catalyst was applicable to a continuous vapor-flow column reactor, and thus, 3,3,3-trifluoropropene was converted into (S)-2-trifluoromethylpropanal with an iso/normal ratio of 95/5 and 90% ee. Less volatile olefins, such as styrene, vinyl acetate, 1-alkenes, and fluorinated alkenes, were successfully converted into the corresponding isoaldehydes with high ee values, when they were injected through a supercritical CO2-flow column reactor. Successive injection of a series of olefins realized the conversion of an olefin library into an optically active aldehyde library.

Synthesis of New Chiral Phosphinephosphites Having 2-Diphenylphosphinobiphenyl-2'-yl Backbone and Their Use in Rh(I)-Catalyzed Asymmetric Hydroformylations

New chiral phosphinephosphites (R)-(5,5'-dichloro-2-diphenylphosphino-4,4',6,6'-tetramethylbiphenyl-2'-yl)(S)-1,1'-binaphthalen-2,2'-diyl)phosphite and its enantiomer (S,R)-BIPHEMPHOS have been synthesized from 5,5'-dichloro-4,4',6,6'-tetramethyl-2,2'-biphenyldiol in enantiomerically pure form.Their Rh(I) complexes have been shown to be highly efficient catalysts for asymmetric hydroformylations of a variety of olefinic substrates.The corresponding phosphinephosphites derived from 2,2'-biphenyldiol were also tested as ligands for asymmetric hydroformylation.

Asymmetric Hydroformylation of 1,2-Disubstituted Olefins Catalysed by Chiral Phosphinephosphite-Rhodium(I) Complexes

Hydroformylations of internal olefins such as (E)- and (Z)-but-2-ene, (E)- and (Z)-1-phenylprop-1-ene, indene, and 1,2-dihydronaphthalene catalysed by (R,S)-binaphos-RhI complex phosphite> or its enantiomer gave the corresponding oxoaldehydes in up to 97percent enantiomeric excess, e.e.

TOTAL SYNTHESIS OF (-)-BETAENONE C

Stereoselctive synthesis of (-)-betaenone C through intramolecular Diels-Alder reaction has made possible to provide pertinent intermediates for the biosynthetic study of betaenones.