85269-23-4

Usage

InChI:InChI=1/C21H36O5/c1-7-12(2)17-20(5,15(23)8-9-22)16-13(3)10-19(4,25)11-14(16)18(24)21(17,6)26/h12-14,16-17,22,25-26H,7-11H2,1-6H3/t12-,13-,14+,16+,17-,19-,20-,21+/m1/s1

Upstream product

• 106-25-2 Nerol 
• 127760-69-4 (2E, 4R)-2,4-dimethyl-2-hexen-1-ol 
• 127718-15-4 (R)-5-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-5-methyl-dihydro-furan-2-one 
• 127718-16-5 (3R,5R)-5-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3,5-dimethyl-dihydro-furan-2-one 
• 115473-44-4 (-)-Probetaenone 
• 76985-26-7 (2S,3R)-3,7-dimethyl-2,3-epoxy-6-octen-1-ol 
• 116-53-0 (-)-2-methylbutyric acid 
• 127760-70-7 (R,E)-2,4-dimethylhex-2-enal 18 
• 96-17-3 (-)-2-methylbutanal 
• 127718-21-2 C₃₇H₄₄O₆S 
• 127718-20-1 C₃₇H₄₄O₄S 
• 127718-22-3 C₃₉H₅₂O₄ 
• 127718-19-8 tert-Butyl-[(3R,5R)-3-(2-methoxy-ethoxymethoxy)-3,5-dimethyl-6-trityloxy-hexyloxy]-dimethyl-silane 
• 127718-25-6 1-[(1R,2S,4aR,6R,8R,8aS)-2-sec-Butyl-6-(2-methoxy-ethoxymethoxy)-1,3,6,8-tetramethyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-3-methoxy-propan-1-one 

Downstream Products

• 85269-22-3 betaenone A 
• 85269-25-6 (-)-betaenone C 
• 85269-24-5 betaenone F 

Relevant academic research and scientific papers

Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis

A unique highly reducing polyketide synthase (HR-PKS) with a reductase domain was identified in a betaenone biosynthetic gene cluster. Successful heterologous expression and characterization of the HR-PKS and trans-acting enoyl reductase (ER) provide insights into the core structure formation with a decalin scaffold and allow reconstitution of the betaenone biosynthetic machinery.

TOTAL SYNTHESIS OF (-)-BETAENONE C

Stereoselctive synthesis of (-)-betaenone C through intramolecular Diels-Alder reaction has made possible to provide pertinent intermediates for the biosynthetic study of betaenones.