33224-80-5 Usage
Description
2-Ethoxy-2-(2-naphthyl)acetonitrile is an organic compound that serves as a novel substrate for Cytochrome P450, a group of enzymes involved in the metabolism of various substances in the body. Its unique structure allows it to be suitable for fluorescence assays, making it a valuable tool in research and development.
Uses
Used in Research and Development:
2-Ethoxy-2-(2-naphthyl)acetonitrile is used as a substrate for Cytochrome P450 in fluorescence assays, allowing researchers to study the enzyme's activity and its role in various biological processes. This application is crucial for understanding the metabolism of drugs, toxins, and other substances, as well as for developing new drugs and therapies.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Ethoxy-2-(2-naphthyl)acetonitrile is used as a tool to evaluate the effectiveness of Cytochrome P450 enzymes in metabolizing drugs. This helps in the development of new drugs with improved pharmacokinetics and reduced side effects, ultimately benefiting patients and healthcare providers.
Check Digit Verification of cas no
The CAS Registry Mumber 33224-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,2,2 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 33224-80:
(7*3)+(6*3)+(5*2)+(4*2)+(3*4)+(2*8)+(1*0)=85
85 % 10 = 5
So 33224-80-5 is a valid CAS Registry Number.
33224-80-5Relevant articles and documents
Design, synthesis and evaluation of novel P450 fluorescent probes bearing α-cyanoether
Zhang, Rong,Kang, Kyung-Don,Shan, Guomin,Hammock, Bruce D.
, p. 4331 - 4334 (2007/10/03)
Four α-cyano-containing ethers based on 2-alkoxy-2-naphthylacetonitriles have been designed as a novel structural class of cytochrome P450 fluorescent probes. Their syntheses, fluorescence properties and evaluation in the fluorogenic assay of cytochrome P