33263-07-9

Upstream product

• 34897-85-3 o-azidobenzoyl chloride 
• 62-53-3 aniline 
• 21563-73-5 2-aminobenzoyl chloride 
• 19263-30-0 3-phenyl-1,2,3-benzotriazin-4(3H)-one 
• 4424-17-3 2-aminobenzanilide 
• 16714-25-3 2-azidobenzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 
• 118-92-3 anthranilic acid 
• 31162-13-7 2-azidobenzoic acid 

Downstream Products

• 4424-17-3 2-aminobenzanilide 
• 3682-71-1 2-phenyl-2H-indazole 
• 88279-19-0 3-ethoxy-2-phenyl-2H-indazole 
• 88279-20-3 2-phenyl-3-pyrrolidinyl-2H-indazole 
• 88279-21-4 3-chloro-2-(p-nitrophenyl)-5-nitro-2H-indazole 
• 1182783-55-6 1-benzyl-2-phenyl-1H-indazol-3(2H)-one 
• 1182783-63-6 1-(4-methylbenzyl)-2-phenyl-1H-indazol-3(2H)-one 
• 1182783-59-0 1-(4-chlorobenzyl)-2-phenyl-1H-indazol-3(2H)-one 
• 1182783-61-4 1-(4-bromobenzyl)-2-phenyl-1H-indazol-3(2H)-one 
• 1182783-84-1 1-(4-nitrophenyl)-2-phenyl-1H-indazol-3(2H)-one 
• 1182783-57-8 1-(4-fluorobenzyl)-2-phenyl-1H-indazol-3(2H)-one 
• 1182783-65-8 1-(4-nitrobenzyl)-2-phenyl-1H-indazol-3(2H)-one 
• 70704-39-1 3-chloro-2-phenyl-2H-indazole 

Relevant academic research and scientific papers

NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides

An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramolecular cyclization.

Synthesis of Diverse Nitrogen Heterocycles via Palladium-Catalyzed Tandem Azide–Isocyanide Cross-Coupling/Cyclization: Mechanistic Insight using Experimental and Theoretical Studies

A rapid and elegant tandem azide–isocyanide cross-coupling/cyclization protocol has been developed based on a nitrene transfer reaction. The palladium-catalyzed ligand-free methodology led to the synthesis of three different heterocyclic scaffolds with excellent atom/step/redox economy. Studies based on first-principles-based quantum calculations and control experiments unraveled a concerted process of nitrene transfer reaction on isocyanides, ruling out the metallaaziridine intermediate reported earlier. This finding could pave the way for novel applications of nitrene transfer reactions to generate bioactive heterocycles. (Figure presented.).

An efficient one-pot strategy for the synthesis of triazole-fused 1,4-benzodiazepinones from n-substituted 2-azidobenzamides

A catalyst-free, one-pot strategy for the synthesis of 1,2,3-triazole-fused 1,4-benzodiazepinone derivatives from N-substituted 2-azidobenzamides and propargyl bromide, in the presence of a base, is reported. The products are formed in good to excellent y

Microwave-assisted base-catalyzed cyclization and nucleophilic substitution of o-azidobenzanilides to synthesize 1,2-disubstituted indazol-3-ones

A series of 1,2-disubstituted indazol-3-ones were synthesized by microwave-assisted base-catalyzed cyclization and nucleophilic substitution of o-azidobenzanilides. Among five tested reaction conditions, the cyclization of o-azidobenzanilides catalyzed by