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Usage

Uses

Used in Scientific Research:
Gulonolactone is used as a research compound for studying vitamin C metabolism and its physiological effects on health. It helps researchers understand the processes involved in the synthesis of ascorbic acid and the role of vitamin C in various biological functions.
Used in Pharmaceutical Industry:
Gulonolactone is used as a precursor in the production of vitamin C supplements and pharmaceutical formulations. It is an essential component in the synthesis of ascorbic acid, which is then used to create various vitamin C products that cater to the dietary needs of humans and other animals that cannot produce gulonolactone naturally.
Used in Nutritional Supplements:
Gulonolactone is used as an ingredient in nutritional supplements to provide a source of vitamin C for individuals who may not be getting enough through their diet. It is particularly important for those who have a genetic inability to produce gulonolactone, ensuring they receive the necessary amount of vitamin C for optimal health.
Used in Food Industry:
Gulonolactone is used as a food additive to fortify products with vitamin C, enhancing their nutritional value. This is especially relevant for products that may have a high risk of vitamin C deficiency in the population, such as certain fruit juices or dietary supplements.

Upstream product

• 133-42-6 galactonic acid 
• 19242-59-2 D-galactose N,N'-diphenylformazan 
• 608-66-2 D-galactitol 
• 69-65-8 mannitol 

Downstream Products

• 133-42-6 gluconic acid 
• 50-99-7 galactose 
• 121570-26-1 1-(3-chlorophenyl)-3-(1,2,3-tri-O-acetyl-L-threo-glycerol-1-yl)-4,5-pyrazoledione 4-(3-chlorophenylhydrazone) 
• 89912-70-9 5-O-acetyl-3,6-anhydro-3-C-(3-chlorophenylazo)-L-xylo-2-hexulosono-1,4-lactone 2-(3-chlorophenylhydrazone) 
• 89912-64-1 L-threo-2,3-hexodiulosono-1,4-lactone 2,3-bis(3-chlorophenylhydrazone) 
• 89912-69-6 3,6-anhydro-3-C-(3-chlorophenylazo)-L-xylo-2-hexulosono-1,4-lactone 2-(3-chlorophenylhydrazone) 
• 89912-66-3 1-(3-chlorophenyl)-3-(L-threo-glycerol-1-yl)-4,5-pyrazoledione 4-(3-chlorophenylhydrazone) 
• 89912-65-2 4-(2-acetoxyethylidene)-4-hydroxy-2,3-dioxobutano-1,4-lactone 2-(3-chlorophenylhydrazone) 
• 89912-63-0 L-threo-2,3-hexodiulosono-1,4-lactone 2-(3-chlorophenylhydrazone) 
• 490-83-5 L-threo-2,3-hexodiulosono-1,4-lactone 
• 40656-50-6 2,3:5,6-di-O-cyclohexylidene-D-gulonic acid γ-lactone 
• 643-01-6 L-mannitol 
• 1426415-12-4 (3S,4R,6S)-3,4-O-isopropylidene-6-(tosyloxymethyl)tetrahydro-2H-pyran-3,4-diol 
• 1426415-10-2 (3S,4R,6S)-3,4-O-isopropylidene-6-(3,5-dinitrobenzoyloxymethyl)tetrahydro-2H-pyran-3,4-diol 

Relevant academic research and scientific papers

A new efficient access to glycono-1,4-lactones by oxidation of unprotected itols by catalytic hydrogen transfer with RhH(PPh3)4-benzalacetone system

Treatment of unprotected pentitols and hexitols with RhH(PPh3)4-benzalacetone system leads exclusively to glycono-1,4-lactones in 60-96% yield.

2-Acetamido-2-deoxyaldonolactones from sugar formazans

A new approach towards simple aldonic acid derivatives starting from the corresponding aldoses via the 2-acetamido-2-deoxy formazans resulted in the synthesis of 2-acetamido-2-deoxy-D-galactono-1,4-lactone (8), and its 6-deoxy (11) and 6-azido-6-deoxy (14) analogues on treatment with trifluoroacetic acid.The five-membered ring structure of the lactones and that of the intermediate lactone phenylhydrazone (7) was proved by 1H and 13C NMR studies, including deuterium-induced differential isotope shift (DIS) measurements.With sodium borohydride, lactones 8 and 11 were converted into 2-acetamido-2-deoxy-D-galactitol (15) and its 6-deoxy analogue (17), respectively.