332884-35-2

Basic information

• Product Name: 2-AMINO-6-PYRIDINE CARBOXALDEHYDE
• Synonyms: 2-AMINO-6-PYRIDINE CARBOXALDEHYDE;2-Pyridinecarboxaldehyde,6-amino-(9CI);6-Amino-2-pyridinecarboxaldehyde;6-AMinopyridine-2-carbaldehyde;6-aMinopicolinaldehyde;2-Pyridinecarboxaldehyde, 6-aMino-
• CAS NO: 332884-35-2
• Molecular Formula: C₆H₆N₂O
• Molecular Weight: 122.12
• Product Categories: PYRIDINE
• Mol File: 332884-35-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 272℃
• Flash Point: 118℃
• Appearance: /
• Density: 1.264
• Vapor Pressure: 0.00616mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.50±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-6-PYRIDINE CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6-PYRIDINE CARBOXALDEHYDE(332884-35-2)
• EPA Substance Registry System: 2-AMINO-6-PYRIDINE CARBOXALDEHYDE(332884-35-2)

Safety Data

• Hazardous Substances Data: 332884-35-2(Hazardous Substances Data)

Usage

General Description

2-Amino-6-pyridine carboxaldehyde is a chemical compound with the molecular formula C6H7N2O. It is an aromatic aldehyde derivative with a pyridine ring and an amino group attached to the carbon in the 2-position. 2-AMINO-6-PYRIDINE CARBOXALDEHYDE is commonly used in the synthesis of pharmaceuticals, agrochemicals, and dyes. It also has potential applications in the development of new organic materials and as a building block in organic synthesis. Additionally, 2-amino-6-pyridine carboxaldehyde has been studied for its potential biological activity and is a subject of interest for medicinal and pharmaceutical research.

InChI:InChI=1/C6H6N2O/c7-6-3-1-2-5(4-9)8-6/h1-4H,(H2,7,8)

Upstream product

• 153140-22-8 2-tritylaminopyridine-6-carbaldehyde 
• 1211530-61-8 6-amino-N-methoxy-N-methylpicolinamide 
• 23628-31-1 6-aminopicolinic acid 
• 153140-21-7 Ethyl 6-tritylaminopicolinate 
• 69142-64-9 ethyl 6-aminopicolinate 

Relevant articles and documents

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS

Provided herein are novel substituted bridged urea and related analogs and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Synthesis, characterization, photoinduced isomerization, and spectroscopic properties of vinyl-1,8-naphthyridine derivatives and their copper(I) complexes

A series of 1,8-naphthyridine derivatives containing vinyl, 2-(2-acetylamino-pyridine-6-ethylene)-4-methyl-7-acetylamino-1,8-naphthyridine (L1), 2-(2-acetylamino-pyridine-6-ethylene)-1,8-naphthyridine (L 2), 2-(2-acetylamino-pyridinyl-6-ethylene)-4-methyl-7-hydroxyl-1,8- naphthyridine (L3), 2-(2-diacetylamino-pyridinyl-3-ethylene)-7- diacetylamino-1,8-naphthyridine (L4), and 7-(2-diacetylamino- pyridinyl-3-ethylene)-4′-acetyl-pyrrolo[1′,5′-a]-1, 8-naphthyridine (L5), as well as complexes [CuL1(PCy 3)](BF4)2 (1) (PCy3 = tricyclohexylphosphine), [Cu2L1(PPh3) 4](BF4)2 (2) (PPh3 = triphenylphosphine), [Cu2L1(dppm)](BF4) 2 (3) (dppm = bis(diphenylphosphino)methane), and [Cu 2(L1)(dcpm)][BF4]2 (4) (dcpm = bis(dicyclohexylphosphino)methane, were synthesized. All these compounds, except for L1 and L2, were characterized by single crystal X-ray diffraction analysis, and a comprehensive study of their spectroscopic properties involving experimental theoretical studies is presented. We found an intramolecular 1,3-hydrogen transfer during the formation of L3 and L4, which in the case of the latter plays an important role in the 1,5-dipolar cyclization of L5. The spectral changes that originate from an intramolecular charge transfer (ICT) in the form of a πpy→π*napy transition can be tuned through acid/base-controlled switching for L1-L3. A photoinduced isomerization for L1-L3, 1, and 2 having flexible structures was observed under 365 nm light irradiation. Quantum chemical calculations revealed that the dinuclear complexes with structural asymmetry exhibit different metal-to-ligand charge-transfer transitions.