332949-32-3Relevant academic research and scientific papers
A novel cardenolide photoaffinity label for the Na/K-ATPase
Zotzmann, J?rg,Hennig, Lothar,Welzel, Peter,Müller, Dietrich,Sch?fer, Claudia,Zillikens, Stefan,Pusch, Hermann,Glitsch, Helfried G.,Regenthal, Ralf
, p. 9625 - 9632 (2000)
A benzoylbenzoyloxy derivative of digitoxigenin has been prepared which is the first cardenolide with an affinity label in the lactone ring. It inhibits the Na+/K+-ATPase almost as effectively as digitoxigenin itself. The activity was lost when in addition a biotin tag was attached to ring A. (C) 2000 Elsevier Science Ltd.
