3330-25-4

Basic information

• Product Name: (E)-4-chloro-2-methyl-but-2-enal
• Synonyms: (E)-4-chloro-2-methyl-but-2-enal;2-Butenal, 4-chloro-2-Methyl-
• CAS NO: 3330-25-4
• Molecular Formula: C₅H₇ClO
• Molecular Weight: 118.56
• Mol File: 3330-25-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 194.6 °C at 760 mmHg
• Flash Point: 73.5 °C
• Appearance: /
• Density: 1.047 g/cm³
• Vapor Pressure: 0.438mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: (E)-4-chloro-2-methyl-but-2-enal(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-chloro-2-methyl-but-2-enal(3330-25-4)
• EPA Substance Registry System: (E)-4-chloro-2-methyl-but-2-enal(3330-25-4)

Safety Data

• Hazardous Substances Data: 3330-25-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 1648, 1976 DOI: 10.1021/jo00871a039Tetrahedron Letters, 14, p. 1719, 1973

InChI:InChI=1/C5H7ClO/c1-5(4-7)2-3-6/h2,4H,3H2,1H3/b5-2+

Upstream product

• 1838-94-4 isoprene epoxide 
• 10523-96-3 3-methyl-3-butenyl chloride 
• 503-60-6 3,3-dimethyl-allyl chloride 

Downstream Products

• 104199-13-5 (2E,4Z)-6-Chloro-4-methyl-hexa-2,4-dienoic acid 
• 104293-66-5 ((1R,4aS,8S,8aS)-8-Hydroxy-2,5,8a-trimethyl-7-oxo-1,4,4a,7,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 104199-22-6 (3aS,6aS,9aR,9bS)-9-Methoxy-4,9b-dimethyl-3,3a,6,6a,9a,9b-hexahydro-benzo[de]chromene-2,7-dione 
• 104199-27-1 ((1R,4aS,8S,8aS)-8-Hydroxy-8a-methoxymethyl-2,5-dimethyl-7-oxo-1,4,4a,7,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 104199-24-8 (3aS,6aS,9aR,9bS)-9-Methoxy-9b-methoxymethyl-4-methyl-3,3a,6,6a,9a,9b-hexahydro-benzo[de]chromene-2,7-dione 
• 104199-20-4 ((1S,4aS,8R,8aS)-8-Hydroxy-7-methoxy-8a-methoxymethyl-2-methyl-5-oxo-1,4,4a,5,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 104199-03-3 (3aS,6aR,9aS,9bR)-4,7,9b-Trimethyl-3,3a,6,6a,9a,9b-hexahydro-benzo[de]chromene-2,9-dione 
• 104319-34-8 (3aS,6aR,9aS,9bR)-9b-Methoxymethyl-4,7-dimethyl-3,3a,6,6a,9a,9b-hexahydro-benzo[de]chromene-2,9-dione 
• 104199-05-5 (3aS,6aR,9aR,9bR)-9b-Methoxymethyl-4,7-dimethyl-3,3a,6,6a,9a,9b-hexahydro-benzo[de]chromene-2,9-dione 
• 104199-11-3 ((1R,4aR,8aR)-7-Methoxy-2,8a-dimethyl-5,8-dioxo-1,4,4a,5,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 104199-08-8 ((1R,4aS,8aR)-7-Methoxy-2,8a-dimethyl-5,8-dioxo-1,4,4a,5,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 104199-10-2 ((1S,4aS,8aS)-7-Methoxy-8a-methoxymethyl-2-methyl-5,8-dioxo-1,4,4a,5,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 104265-19-2 ((1S,4aR,8aS)-7-Methoxy-8a-methoxymethyl-2-methyl-5,8-dioxo-1,4,4a,5,8,8a-hexahydro-naphthalen-1-yl)-acetic acid 
• 14918-80-0 3-methyl-4-oxobut-2-enyl acetate 

Relevant articles and documents

Efficient and stable small molecule agonist of v [gamma] 9v delta 2t cells

The invention relates to a formula (I) compound as an efficient and stable small molecule agonist of v [gamma] 9v delta 2t cells, wherein the groups are defined in the specification and the claims. The present invention also relates to pharmaceutical compositions containing the formula (I) compound and use thereof in the treatment of proliferative diseases.

Preparation method of 4-acetoxy-2-methyl-2-crotonaldehyde

The invention provides a preparation method of 4-acetoxy-2-methyl-2-crotonaldehyde. The preparation method comprises the following steps that (1) prenyl chloride is oxidized with oxygen under the effect of a catalyst into 4-chloro-2-methyl-2-crotonaldehyde; and 2) 4-chloro-2-methyl-2-crotonaldehyde and acetate are reacted to obtain 4-acetoxy-2-methyl-2-crotonaldehyde. The method is cheap and available in prenyl chloride as a starting material and short in process route as well as is economic and effective.