33328-12-0

Basic information

• Product Name: 4-chlorophenyl N,N-dimethyl-N'-phenylcarbamimidothioate
• Synonyms: 4-chlorophenyl N,N-dimethyl-N'-phenylcarbamimidothioate
• CAS NO: 33328-12-0
• Molecular Weight: 290.817
• Mol File: 33328-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chlorophenyl N,N-dimethyl-N'-phenylcarbamimidothioate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chlorophenyl N,N-dimethyl-N'-phenylcarbamimidothioate(33328-12-0)
• EPA Substance Registry System: 4-chlorophenyl N,N-dimethyl-N'-phenylcarbamimidothioate(33328-12-0)

Safety Data

• Hazardous Substances Data: 33328-12-0(Hazardous Substances Data)

Upstream product

• 1679-18-1 4-Chlorophenylboronic acid 
• 705-62-4 N,N-dimethyl-N'-phenylthiourea 

Relevant articles and documents

An Efficient Chan–Lam S-Arylation of Arylthioureas with Arylboronic Acids

A convenient and efficient protocol has been developed for the preparation of aryl-isothioureas based on the Chan–Lam C–S coupling reaction. The desired aryl-isothioureas were synthesized in good yields (up to 95 %) in the presence of Cu(OAc)2·H2O as catalyst and bipyridine as ligand. A variety of functional groups on the aryl-thiourea and arylboronic acid reagents are tolerated. The method features mild reaction conditions and good yields, thereby illustrating its practical synthetic value in organic synthesis.