33328-23-3Relevant academic research and scientific papers
N-arylation by aryl isocyanates as a general reaction: Useful route to disubstituted S,N-diarylisothioureas
Katritzky, Alan R.,Xiaohong, Cai,Vvedensky, Vladimir Y.,Rogovoy, Boris V.,Forood, Behrouz,Hebert, Normand
, p. 1799 - 1806 (2002)
N-Arylation of guanidines, isoureas and isothioureas by aryl isocyanates is demonstrated to have generality. Novel N′-arylations of S-arylisothioureas (16) with aryl isocyanates provide a new general route to biologically active S,N′-diarylisothioureas (13). Formation of (13) is explained as [2+2] cycloaddition of isoureas (16) to isocyanates followed by elimination of HNCO.
A mild one-pot synthesis of S-aryl carbamimidothioates using diazonium salts under catalyst-free condition
Khalili, Gholamhossein
, p. 1891 - 1894 (2015)
A simple, new method for the synthesis of S-aryl carbamimidothioates is described using aryl diazonium fluoroborates, aryl isothiocyanates, amines, and Et3N as the base at room temperature.
