333309-74-3

Basic information

• Product Name: Benzene, 1-[(1E)-2-bromoethenyl]-2-chloro-
• CAS NO: 333309-74-3
• Molecular Formula: C8H6BrCl
• Molecular Weight: 217.493
• Mol File: 333309-74-3.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(1E)-2-bromoethenyl]-2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(1E)-2-bromoethenyl]-2-chloro-(333309-74-3)
• EPA Substance Registry System: Benzene, 1-[(1E)-2-bromoethenyl]-2-chloro-(333309-74-3)

Safety Data

• Hazardous Substances Data: 333309-74-3(Hazardous Substances Data)

Upstream product

• 2039-87-4 2-chlorostyrene 
• 704-96-1 trans-2-chlorocinnamic acid 
• 3752-25-8 o-chlorocinnamic acid 
• 1355094-04-0 (E)-2-(2-chlorostyryl)-4,4,5,5-tetramethyl-1,3-dioxa-2-borolane 
• 72702-57-9 2-Bromo-1-(2-chlorophenyl)ethan-1-ol 
• 401514-40-7 1-chloro-2-(2,2-dibromovinyl)benzene 
• 1034-49-7 (bromomethyl)triphenyl phosphonium bromide 
• 89-98-5 2-chloro-benzaldehyde 
• 24654-07-7 (2RS,3SR)-2,3-dibromo-3-(2-chlorophenyl)propanoic acid 

Downstream Products

• 1201221-08-0 C₁₇H₁₃ClO 
• 1085710-25-3 (E)-1-chloro-2-(2-iodovinyl)benzene 
• 1467023-74-0 (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-{[(E)-2-chlorostyryl]thio}tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 51220-00-9 (E)-3-(2-chlorophenyl)-2-propenenitrile 

Relevant articles and documents

Metal-Mediated Debromination of gem-Dibromoalkenes under Mild Conditions

We describe the facile and efficient metal-promoted reduction of C-Br bonds of gem-dibromides. When the reaction is mediated by indium, the corresponding vinyl bromides are obtained in good yields and high E-stereoselectivities. Alternatively, when the reduction is mediated by samarium diiodide, vinyl bromides are obtained in moderate yields and good Z-selectivities.

Method for synthesizing beta-bromostyrene through metal-free catalysis

The invention discloses a method for synthesizing beta-bromostyrene through metal-free catalysis, and belongs to the technical field of organic chemistry. Substituted styrene 1 is used as a raw material and is reacted in the presence of a bromination reagent, sodium persulfate and dichloroethane, and the beta-bromostyrene compound 2 can be obtained in one step. The method is capable of solving thetechnical problem that in the traditional synthesis method, conversion into alkenyl boron, alkenyl silicon and other intermediates under the catalysis of noble metals and then further halogenation are needed; the defects of expensive reaction reagent, high catalytic cost, complex operation, incapability of large-scale preparation and the like in the traditional preparation method are avoided; byadopting the method, a series of beta-bromostyrene compounds can be obtained, and the method has a potential application prospect.

Stereoselective Synthesis of Vinyl Iodides through Copper(I)-Catalyzed Finkelstein-Type Halide-Exchange Reaction

An efficient method for the stereoselective synthesis of vinyl iodides is described. The reactions of vinyl bromides with potassium iodide proceed smoothly in the presence of a copper catalyst under mild reaction conditions to produce the corresponding vinyl iodides stereospecifically and in satisfactory to excellent yields.