33332-30-8

Usage

Uses

Used in the Food Industry:
2-CHLORO-6-METHOXYPYRAZINE is used as a flavoring agent for imparting savory and meaty flavors to various food products. Its natural presence in certain fruits and vegetables contributes to their distinct aroma and taste, enhancing the overall sensory experience of these foods.
Used in Agricultural and Pest Control Applications:
2-CHLORO-6-METHOXYPYRAZINE is studied for its potential as an insecticide and repellent due to its strong odor and toxic properties. This makes it a candidate for controlling and repelling pests in agricultural settings, thereby protecting crops and improving yield.
It is crucial to handle 2-CHLORO-6-METHOXYPYRAZINE with care due to its potential to cause irritation to the skin, eyes, and respiratory system if not properly managed. This underscores the importance of safety measures in its application across different industries.

InChI:InChI=1/C5H5ClN2O/c1-9-5-3-7-2-4(6)8-5/h2-3H,1H3

Upstream product

• 23902-69-4 3-methoxypyrazine 1-oxide 
• 32046-05-2 2-methoxypyrazine 1-oxide 
• 4774-14-5 2,6-dichloropyrazine 
• 124-41-4 sodium methylate 

Downstream Products

• 181582-00-3 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(5-chloro-3-methoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol 
• 960503-91-7 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine 
• 181581-95-3 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-chloro-3-methoxy-pyrazine 
• 872355-80-1 C₆H₅ClN₂O₃ 
• 1378822-06-0 C₆H₅ClN₂O₃ 
• 1425045-00-6 C₂₂H₂₀N₄O₂ 
• 934346-27-7 6-methoxypyrazin-2-ylboronic acid 
• 67602-09-9 2-methoxy-6-phenylpyrazine 
• 1644057-79-3 2-methoxy-6-(4-methoxyphenyl)pyrazine 

Relevant academic research and scientific papers

An unexpected synthesis of 7-azidofurazano[3,4-b]tetrazolopyrazine

In the course of our program focused on the preparation of high-nitrogen content heterocyclic compounds, we wish to report an original synthesis of the tricyclic 7-azidofurazano[3,4-b]tetrazolopyrazine via an unprecedented reaction between 2,6-dimethoxy-3,5-dinitropyrazine and hydrazine hydrate. This compound was identified by an X-ray diffraction analysis. Further studies of its structure by 15N and 13C NMR spectroscopy were carried out in different solvents. This allowed us to observe a noteworthy equilibrium involving three forms resulting from the reversible opening of a tetrazole ring.

Studies on Pyrazines. 29. High Regioselective Synthesis of Chloropyrazines from 3-Substituted Pyrazine 1-Oxides

Reaction of 3-methoxy- or 3-chloropyrazine 1-oxides with refluxing phosphoryl chloride in the presence of amine led to a high regioselective formation of 3-substituted 2-chloropyrazines.In contrast, the use of chloroacetyl chloride instead of phosphoryl chloride enabled different regioselectivity to yield 6-substituted 2-chloropyrazines, particularly 3-methoxycarbonylpyrazine 1-oxide was almost exclusively converted into methyl 6-chloropyrazinecarboxylate under conditions without the amine.