333355-35-4Relevant academic research and scientific papers
Pd(OH)2/C (Pearlman's catalyst): A highly active catalyst for Fukuyama, Sonogashira, and Suzuki coupling reactions
Mori, Yoshikazu,Seki, Masahiko
, p. 1571 - 1574 (2007/10/03)
Treatment of thiol esters 1 with zinc reagent 2 in the presence of a small amount (2/C (Pearlman's catalyst) provided functionalized asymmetrical ketones 3 in high yields. The use of Pd(OH)2/C was
Palladium on charcoal-catalyzed Fukuyama coupling reaction
Shimizu, Toshiaki,Seki, Masahiko
, p. 429 - 432 (2007/10/03)
The Pd/C-catalyzed coupling reactions of thiol esters 1 with a zinc reagent 2 were accomplished in the presence of DMF leading to the polyfunctional ketones 3 in good yields under mild reaction conditions. The protocol was applied to the coupling reaction of a thiolactone 4c with a zinc reagent 2 to provide, after dehydration, a dehydrobiotin derivative 5c in 94% yield.
