333358-29-5Relevant academic research and scientific papers
Discovery of new selective butyrylcholinesterase (BCHE) inhibitors with anti-Aβ aggregation activity: Structure-based virtual screening, hit optimization and biological evaluation
Jiang, Cheng-Shi,Ge, Yong-Xi,Cheng, Zhi-Qiang,Wang, Yin-Yin,Tao, Hong-Rui,Zhu, Kongkai,Zhang, Hua
, (2019)
In this study, a series of selective butyrylcholinesterase (BChE) inhibitors was designed and synthesized from the structural optimization of hit 1, a 4-((3,4 -dihydroisoquinolin-2(1H)-yl)methyl)benzoic acid derivative identified by virtual screening our
