333366-23-7

Basic information

• Product Name: N3-Asp(tBu)-OH (dicyclohexylammonium) salt
• Synonyms: (S)-(-)-4-tert-Butyl hydrogen 2-azidosuccinate (dicyclohexylammonium) salt;(S)-2-Azidobutanedioic acid 4-tert-butyl ester (dicyclohexylammonium) salt;(S)-2-Azidosuccinic acid 4-tert-butyl ester (dicyclohexylammonium) salt;Azido-Asp(tBu)-OH (dicyclohexylammonium) salt;N3-Asp(tBu)-OH (dicyclohexylammonium) salt
• CAS NO: 333366-23-7
• Molecular Formula: C₈H₁₃N₃O₄
• Molecular Weight: 215.21
• Product Categories: Aspartic Acid Derivatives;Aliphatic Azides;Alkynes and Other Reagents;Amino Acid Azides/Alkynes;Asymmetric Synthesis;Azides;Building Blocks;Chemical Biology;Chemical Synthesis;Chiral Building Blocks;Conjugation Chemistry: Azides;Nitrogen Compounds;Organic Building Blocks;Peptide Chemistry;Unnatural Amino Acid Derivatives
• Mol File: 333366-23-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 34-38℃
• Appearance: /
• BRN: 8765080
• CAS DataBase Reference: N3-Asp(tBu)-OH (dicyclohexylammonium) salt(CAS DataBase Reference)
• NIST Chemistry Reference: N3-Asp(tBu)-OH (dicyclohexylammonium) salt(333366-23-7)
• EPA Substance Registry System: N3-Asp(tBu)-OH (dicyclohexylammonium) salt(333366-23-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 333366-23-7(Hazardous Substances Data)

Usage

Uses

(2S)-Azidobutanedioic Acid 4-(1,1-Dimethylethyl) Ester is a reagent used in the preparation of acyclic nucleoside phosphonates which contain 0-deazahypoxanthine for inhibition of plasmodial 6-oxopurine phosphoribosyltransferases.

Upstream product

• 3057-74-7 L-Asp(t-Bu) 

Downstream Products

• 103060-53-3 daptomycin 
• 1189342-34-4 tert-butyl (S)-3-azido-4-oxo-4-{[3-(triisopropylsilyl)-prop-2-ynyl]amino}butanoate 

Relevant articles and documents

BENZODIAZEPINES AS BROMODOMAIN INHIBITORS

The present invention provides novel benzodiazepine derivatives of Formula I or pharmaceutically acceptable derivatives, polymorphs, salts or prodrugs thereof. Said compounds have potential as bromodomain (BRD) inhibitors.

Solid-phase Staudinger ligation from a novel core-shell-type resin: A tool for facile condensation of small peptide fragments

Solid-phase Staudinger ligation of small peptides was performed on a novel core-shell-type resin. Solid-phase Staudinger ligation was mediated by synthetic solid-supported phosphinothiol, which was readily prepared by a straightforward synthetic route. This protocol afforded final peptide products in excellent yields and purities and thus could provide the opportunity to facilitate a simple manipulation for condensation of peptide fragments. In particular, the resulting resin could be recycled in a successful manner.