333383-79-2Relevant academic research and scientific papers
Novel method for construction of tetrahydro-1-benzazepine and tetrahydro-2-benzazepine based on 7-endo selective Friedel-Crafts cyclization of vinyloxirane
Mizukami, Megumi,Wada, Koji,Sato, Gen,Ishii, Yusuke,Kawahara, Norio,Nagumo, Shinji
, p. 4120 - 4138 (2013/06/26)
The 7-endo Friedel-Crafts cyclization of vinyloxiranes, which have a nitrogen atom at the linker between the aromatic ring and the epoxide, was found to proceed regio- and stereoselectively to afford polyfunctional tetrahydro-1-benzazepine and tetrahydro-
A practical route to quinolines from anilines
Tokuyama, Hidetoshi,Sato, Masashi,Ueda, Toshihiro,Fukuyama, Tohru
, p. 105 - 108 (2007/10/03)
A practical route to quinoline from anilines through acid-mediated cyclization of 3-(N-aryl-N-sulfonylamino)propionaldehydes has been developed. Treatment of the cyclization products, dihydroquinoline intermediates with KOH in DMSO leads to substituted quinolines.
