333418-51-2 Usage
Description
(4-PHENYL-5-PYRIDIN-3-YL-4 H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID is a sulfur-containing organic compound with a complex structure that features a phenyl group (C6H5), a pyridinyl group (C5H4N), and a triazolylsulfanyl moiety attached to an acetic acid residue. Its unique structural features, including aromatic rings and sulfur linkage, suggest potential pharmacological activities, although further scientific research is required to confirm its specific properties and applications.
Uses
Used in Pharmaceutical Industry:
(4-PHENYL-5-PYRIDIN-3-YL-4 H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID is used as a potential pharmaceutical candidate for [specific application reason] due to its structural features that are often found in bioactive molecules.
(Note: The specific application reason is not provided in the materials, so it is left blank for the user to fill in based on further research or information.)
Check Digit Verification of cas no
The CAS Registry Mumber 333418-51-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,3,4,1 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 333418-51:
(8*3)+(7*3)+(6*3)+(5*4)+(4*1)+(3*8)+(2*5)+(1*1)=122
122 % 10 = 2
So 333418-51-2 is a valid CAS Registry Number.
333418-51-2Relevant articles and documents
Synthesis and antimicrobial properties of new thiosemicarbazide, 1,2,4-triazole, and 1,3,4-thiadiazole derivatives of sulfanylacetic acid
Popiolek, Lukasz,Kosikowska, Urszula,Dobosz, Maria,Malm, Anna
, p. 468 - 481 (2012/04/17)
1,2,4-triazole and 1,3,4-thiadiazole derivatives are still considered a viable lead structure for the synthesis of more efficient antimicrobial agents having a broad spectrum of activity. This study presents the synthesis and antimicrobial evaluation of a new series of substituted 1,2,4-triazole and 1,3,4-thiadiazole derivatives. Reaction of 4-phenyl-5-(pyridin-3-yl)-4H-1,2,4- triazole-3-thione with ethyl bromoacetate yields the corresponding ethyl acetate (1). In the subsequent reaction with 100% hydrazine hydrate, the hydrazide (2) was obtained, which was converted with isothiocyanates to new acyl derivatives of thiosemicarbazide (3a-l). The cyclization of these compounds in alkaline media resulted in the formation of new derivatives of 1,2,4-triazole (4a-i), whereas in acidic media new derivatives of 1,3,4-thiadiazole (5a,b,g) were obtained. All synthesized compounds were screened for their in vitro antimicrobial activities.
