333430-58-3

Upstream product

• 683-57-8 bromo-acetic acid amide 
• 350799-03-0 2-(3-Nitro-benzenesulfonylamino)-acetamide 
• 121-51-7 3-nitrobenzenesulphonyl chloride 

Downstream Products

• 197367-22-9 2-[(3-{4-[3-(bis-carbamoylmethyl-sulfamoyl)-phenylamino]-6-chloro-[1,3,5]triazin-2-ylamino}-benzenesulfonyl)-carbamoylmethyl-amino]-acetamide 
• 197367-35-4 2-[(3-amino-benzenesulfonyl)-carbamoylmethyl-amino]acetamide 

Relevant academic research and scientific papers

The discovery of RFI-641 as a potent and selective inhibitor of the respiratory syncytial virus

The design and synthesis of a new potent and selective inhibitor of the respiratory syncytial virus are described. This compound, RFI-641, emerged from analysis of the structure-activity relationship in a series of biphenyl triazine anionic compounds possessing specific anti-RSV activity. The key synthetic step involves coupling of diaminobiphenyl 11 with two equivalents of chlorotriazine 10 under microwave conditions. RFI-641 inhibited RSV in vitro and in vivo models.