3335-25-9

Upstream product

• 2168-80-1 4-methyldithioic acid 
• 139-02-6 sodium phenoxide 
• 120449-42-5 Se-phenyl 4-methylbenzenecarboselenothioate 
• 60410-77-7 bis(4-methylbenzenethiocarbonyl) sulphide 
• 50684-43-0 4-methylbenzothioic S-acid 

Downstream Products

• 20226-33-9 p-Methyl-thiobenzoyl-isothiocyanat 
• 64956-08-7 C₂₈H₅₀N₂S₂Si₄ 
• 26028-04-6 O-ethyl 4-methylbenzenecarbothioate 
• 15088-74-1 4-methylbenzoic dithioperoxyanhydride 
• 5977-80-0 O-methyl 4-methylbenzenecarbothioate 
• 16112-33-7 2,5-bis(4-methylphenyl)-1,3,4-thiadiazole 
• 42967-76-0 piperidinium 4-methylbenzenecarbodithiolate 
• 64310-34-5 3,4-dihydro-2H-1,3,4-triazole-2-thione 
• 54254-92-1 diethylammonium 4-methylbenzenecarbodithioate 
• 53724-38-2 cyclohexylammonium 4-methylbenzenecarbodithioate 
• 102197-60-4 phenylseleno 4-methyl(thiobenzoyl) sulfide 
• 89916-22-3 hexacarbonyldi-4-tolyl[η2-di(μ2-thiol)ene]dimanganese(Mn-Mn) 
• 76786-76-0 1-cyano-5-<4-(methylthio)benzoyl>-1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole 
• 681440-55-1 4-methylthiobenzoic acid O-(4-nitrophenyl) ester 

Relevant academic research and scientific papers

Se-Aryl Alkane- or Arenecarboselenothioates: Synthesis and Some Reactions

A series of Se-aryl carboselenothioates 3 (RCSSeAr, R=alkyl, aryl) were synthesized and characterized from the reaction of bis(thioacyl) sulfides 1 with sodium areneselenolates.The thionselenolesters 3 are stable (liquid or crystals) both thermally and to moisture.Reactions of 3 with aliphatic primary and secondary amines gave the corresponding ammonium carbodithioates 8 together with diphenyl diselenide 7.In contrast, treatment with aromatic amines or sodium alcoholates afforded the corresponding thioamides or O-alkyl or O-aryl thionoesters in good yields.The oxidation of 3 with m-chloroperbenzoic acid gave the corresponding sulfides 12 and acyl arylseleno sulfides 13 which are formed by a rearrangement of the ArSe group to the thiocarbonyl sulfur atom.

Anti-inflammatory method

Compounds in which 2,6-di(t-butyl)phenol is substituted in the 4 position by an optionally substituted benzoyl group have valuable pharmacological activity as anti-inflammatory agents.

Indenylacetic acid compounds

4, 5, 6 or 7 Aryl substituted indenyl acetic acids and pharmaceutically acceptable salts, amides and esters thereof. The 4, 5, 6 or 7 aryl substituted indenyl acetic acids have anti-inflammatory, anti-pyretic and analgesic activity. The invention also includes methods for the preparation of these compounds, pharmaceutical compositions and methods of treating inflammation by administering these particular compounds to patients.