33350-84-4Relevant academic research and scientific papers
An expedient synthesis strategy to the 1,4-dihydropyridines and pyrido[1,2-a]quinoxalines: iodine catalyzed one-pot four-component domino reactions
Rezvanian, Atieh
, p. 6428 - 6435 (2016/09/23)
Another aspect concerning enaminone chemistry leading to the one-pot synthesis of functionalized novel 1,4-dihydropyridines and pyrido[1,2-a]quinoxalines has been described. By highly efficient, one-pot, iodine-catalyzed four-component reactions, combinin
Hypervalent iodine(iii)-induced oxidative [4+2] annulation of o-phenylenediamines and electron-deficient alkynes: Direct synthesis of quinoxalines from alkyne substrates under metal-free conditions
Okumura, Sota,Takeda, Youhei,Kiyokawa, Kensuke,Minakata, Satoshi
supporting information, p. 9266 - 9268 (2013/10/01)
Hypervalent iodine(iii)-induced oxidative [4+2] annulation of o-phenylenediamines and electron-deficient alkynes under metal-free conditions has been developed. The reaction allows for direct access to quinoxalines bearing two electron-withdrawing groups in an efficient manner.
On water: A practical and efficient synthesis of benzoheterocycle derivatives catalyzed by nanocrystalline copper(II) oxide
Sadjadi, Sodeh,Hekmatshoar, Rahim,Ahmadi, Seyed Javad,Hosseinpour, Morteza,Outokesh, Mohammad
experimental part, p. 607 - 614 (2010/04/04)
Recyclable CuO nanoparticles provide an efficient, economic, and novel method for the synthesis of quinoxaline, benzoxazine, and benzothiazine. This method provides a wide range of substrate applicability, avoids the use of organic solvents, and gives benzoheterocycles in satisfactory yields. Copyright Taylor & Francis Group, LLC.
Ultrasound-promoted greener synthesis of benzoheterocycle derivatives catalyzed by nanocrystalline copper(II) oxide
Sadjadi, Sodeh,Sadjadi, Samaheh,Hekmatshoar, Rahim
experimental part, p. 764 - 767 (2011/10/13)
CuO nanoparticles provide an efficient, economic, and novel method for the synthesis of quinoxaline, benzoxazine, and benzothiazine under ultrasonic irradiation. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst.
An efficient synthesis of functionalized 6,10-dioxo-6,10-dihydro-5H- pyrido[1,2-a]quinoxalines and 6,10-dioxo-6,10-dihydropyrido[2,1-c][1,4] benzoxazines
Yavari, Issa,Souri, Sanaz,Sirouspour, Mehdi,Bayat, Mohammad J.
body text, p. 1921 - 1922 (2010/03/04)
An efficient synthesis of alkyl 8-hydroxy-6,10-dioxo-6,10-dihydro-5H- pyrido[1,2-a]quinoxaline-7-carboxylates and alkyl 8-hydroxy-6,10-dioxo-6,10- dihydropyrido[2,1-c][1,4]benzoxazine-7-carboxylates is described. This involves the reaction between malonyl dichloride and alkyl 2-[3,4-dihydro-3- oxoquinoxaline 2(1H)-ylidene]acetates or alkyl 2-(2-oxo-2H-benzo[b][1,4]oxazin- 3(4H)-ylidene)acetates in CH2Cl2 at room temperature. Georg Thieme Verlag Stuttgart.
Synthesis and Thermal Cyclization Reactions of Methyl Isocrotonate Derivatives
Kawahara, Norio,Shimamori, Takako,Itoh, Tsuneo,Takayanagi, Hiroaki,Ogura, Haruo
, p. 457 - 467 (2007/10/02)
Methyl isocrotonate derivatives prepared from various 1,2-ethylenediamines, o-phenylenediamines, 2-aminoethanols or o-aminophenols with dimethyl acetylenedicarboxylate were easily converted to pyridopyrazines, pyridoquinoxalines, pyrido-1,4-oxazines, pyrido-1,4-benzoxazines, respectively, and other cyclization compounds by means of thermal reactions.Keywords - cyclization; thermal reaction; methyl isocrotonate derivative; X-ray analysis; pyridopyrazine; pyridoquinoxaline; pyrido-1,4-oxazine; pyrido-1,4-benzoxazine; dimethyl acetylenedicarboxylate
