82296-45-5Relevant academic research and scientific papers
Synthesis and oral antiallergic activity of carboxylic acids derived from imidazo[2,1-c][1,4]benzoxazines, imidazo[1,2-a]quinolines, imidazo[1,2-a]quinoxalines, imidazo[1,2-a]quinoxalinones, pyrrolo[1,2-a]quinoxalinones, pyrrolo[2,3-a]quinoxalinones, and
Ager,Barnes,Danswan,Hairsine,Kay,Kennewell,Matharu,Miller,Robson,Rowlands,Tully,Westwood
, p. 1098 - 1115 (2007/10/02)
4H-Imidazo[2,1-c][1,4]benzoxazine-1-carboxylic acid (3) was found to possess potent activity in the IgE-induced rat passive cutaneous anaphylaxis model which may be predictive of clinical antiallergic activity. Compared to disodium cromoglycate (DSCG,1),
Synthesis and Reactions of Some Novel Imidazobenzoxazines and Related Systems
Danswan, Geoff W.,Hairsine, Peter W.,Rowlands, David A.,Taylor, John B.,Westwood, Robert
, p. 1049 - 1058 (2007/10/02)
A novel synthesis of the new 4H-imidazobenzoxazine system (2) has been carried out under two sets of conditions, leading to products with differing functionalities.The effect of substituents on the cyclization step has been investigated and the reactions of the functional groups of the new ring system have been studied.Derivatives of the related 4,5-dihydroimidazobenzoxazepine (3) have also been prepared.
