33358-37-1

Upstream product

• 108-98-5 thiophenol 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 33844-21-2 2-nitro-4-methoxybenzoic acid 

Downstream Products

• 672288-78-7 1-benzenesulfonyl-4-methoxy-2-nitro-benzene 
• 108977-71-5 benzoic acid-(5-methoxy-2-phenylsulfanyl-anilide) 
• 195073-78-0 (3-Bromo-propyl)-(5-methoxy-2-phenylsulfanyl-phenyl)-amine 
• 195073-73-5 3-Bromo-N-(5-methoxy-2-phenylsulfanyl-phenyl)-propionamide 
• 857600-53-4 2-benzenesulfonyl-5-methoxy-aniline 
• 102827-45-2 2-benzenesulfonyl-5-methoxy-phenol 
• 113061-51-1 8-methoxy-11-phenyl-dibenzo[b,f][1,4]thiazepine 
• 110571-75-0 11-phenyl-dibenzo[b,f][1,4]thiazepin-8-ol 
• 95128-27-1 3-methoxy-6-phenylphenanthridine 
• 94210-65-8 6-phenyl-phenanthridin-3-ol 
• 3323-42-0 2-phenylthio-5-methoxyaniline 

Relevant academic research and scientific papers

Aerobic copper-catalyzed decarboxylative thiolation

Copper-catalyzed decarboxylative thiolation using molecular oxygen as the sole oxidant was developed. A variety of aromatic carboxylic acids including 2-nitrobenzoic acids, pentafluorobenzoic acid and several heteroaromatic carboxylic acids undergo efficient thiolation to furnish the aryl sulfides in moderate to excellent yields.

New spermine and spermidine derivatives as potent inhibitors of trypanosoma cruzi trypanothione reductase

Several spermine and spermidine derivatives containing 2-amino diphenylsulfide substituents were prepared and tested for their inhibiting effects on Trypanosoma cruzi trypanothione reductase. IC50 values were assessed between 0.3 and 3 μM. Compound 32 (K(i) = 0.4 μM) is the most potent TR inhibitor described so far.