33365-42-3Relevant articles and documents
Room temperature N-heterocyclic carbene manganese catalyzed selective N-alkylation of anilines with alcohols
Huang, Ming,Li, Yukui,Li, Yinwu,Liu, Jiahao,Shu, Siwei,Liu, Yan,Ke, Zhuofeng
supporting information, p. 6213 - 6216 (2019/06/07)
The first example of room temperature non-noble metal homogeneous system catalyzed selective N-alkylation of anilines with alcohols by a bis-NHC manganese complex is presented. This system was applied to a large range of alcohols and anilines, including biologically relevant motifs and challenging methanol. Experimental and computational studies suggest an outer-sphere mechanism for this NHC-Mn system.