33365-42-3Relevant academic research and scientific papers
Room temperature N-heterocyclic carbene manganese catalyzed selective N-alkylation of anilines with alcohols
Huang, Ming,Li, Yukui,Li, Yinwu,Liu, Jiahao,Shu, Siwei,Liu, Yan,Ke, Zhuofeng
supporting information, p. 6213 - 6216 (2019/06/07)
The first example of room temperature non-noble metal homogeneous system catalyzed selective N-alkylation of anilines with alcohols by a bis-NHC manganese complex is presented. This system was applied to a large range of alcohols and anilines, including biologically relevant motifs and challenging methanol. Experimental and computational studies suggest an outer-sphere mechanism for this NHC-Mn system.
Improved and General Manganese-Catalyzed N-Methylation of Aromatic Amines Using Methanol
Neumann, Jacob,Elangovan, Saravanakumar,Spannenberg, Anke,Junge, Kathrin,Beller, Matthias
supporting information, p. 5410 - 5413 (2017/04/27)
A novel lutidine-based manganese PNP-pincer complex has been synthesized for the selective N-methylation of aromatic amines with methanol. Using borrowing hydrogen methodology, a selection of differently functionalized aniline derivatives is selectively methylated in good yields.
