333743-01-4Relevant academic research and scientific papers
Evaluation of a series of bicyclic CXCR2 antagonists
Walters, Iain,Austin, Caroline,Austin, Rupert,Bonnert, Roger,Cage, Peter,Christie, Mark,Ebden, Mark,Gardiner, Stuart,Grahames, Caroline,Hill, Steven,Hunt, Fraser,Jewell, Robert,Lewis, Shirley,Martin, Iain,Nicholls, David,Robinson, David
, p. 798 - 803 (2008/09/18)
The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement of the aminothiazole ring with a 2-thiazolone alternat
Thiazolo (4,5-D) pyrimidine compounds
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Page/Page column 9, (2008/06/13)
The invention provides certain thiazolopyrimidine compounds of formula (I) or a pharmaceutically acceptable salt or solvate thereof; processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therap
