333788-75-3

Upstream product

• 600728-65-2 (2R,7R)-2-((S)-1-Benzyloxy-propyl)-7-[(Z)-(S)-1-(tert-butyl-dimethyl-silanyloxy)-6-trimethylsilanyl-hex-3-en-5-ynyl]-2,3,6,7-tetrahydro-oxepine 
• 924-41-4 1,5-hexadiene-3-ol 
• 99838-64-9 (4R,5S)-5-benzyloxy-1-hepten-4-ol 
• 558459-27-1 (1R)-1-[(1S)-oxiranyl]-but-3-en-1-ol 
• 108740-35-8 (2S,3S)-3-Benzyloxy-pentane-1,2-diol 
• 334793-69-0 (S)-4-((S)-1-Benzyloxy-propyl)-2,2-dimethyl-[1,3]dioxolane 
• 333788-81-1 (4R,5S)-5-Benzyloxy-hept-1-yn-4-ol 
• 333788-85-5 (2R,7R)-2-((S)-1-Benzyloxy-propyl)-7-(S)-oxiranyl-2,3,6,7-tetrahydro-oxepine 
• 333788-79-7 (2S,3S)-3-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-pentan-2-ol 
• 333788-68-4 (Z)-(3S,4R)-3-Benzyloxy-8-[(2S,3R)-3-(4-methoxy-benzyloxymethyl)-oxiranyl]-oct-6-en-4-ol 
• 333788-84-4 Methanesulfonic acid (R)-1-[(2R,7R)-7-((S)-1-benzyloxy-propyl)-2,3,6,7-tetrahydro-oxepin-2-yl]-2-(4-methoxy-benzyloxy)-ethyl ester 
• 333788-86-6 (Z)-(S)-1-[(2R,7R)-7-((S)-1-Benzyloxy-propyl)-2,3,6,7-tetrahydro-oxepin-2-yl]-5-(tetrahydro-pyran-2-yloxy)-pent-3-en-1-ol 
• 600728-64-1 {(Z)-(S)-1-[(2R,7R)-7-((S)-1-Benzyloxy-propyl)-2,3,6,7-tetrahydro-oxepin-2-yl]-4-iodo-but-3-enyloxy}-tert-butyl-dimethyl-silane 
• 600728-61-8 (2R,7R)-7-((S)-1-Benzyloxy-propyl)-2,3,6,7-tetrahydro-oxepine-2-carbaldehyde 

Downstream Products

• 333788-76-4 (2R,7R)-2-((S)-1-Benzyloxy-propyl)-7-((Z)-(R)-1-chloro-hex-3-en-5-ynyl)-2,3,6,7-tetrahydro-oxepine 

Relevant academic research and scientific papers

Enantioselective total synthesis of (+)-rogioloxepane A

(Matrix presented) The enantioselective synthesis of (+)-rogioloxepane A has been achieved in 21 steps from 1,5-hexadien-3-ol. The key steps in the synthesis are an asymmetric glycolate alkylation leading to the diene 2 and a subsequent ring-closing metat

The first total synthesis of (+)-rogioloxepane A

The first total synthesis of (+)-rogioloxepane A is described. The α,ω-trans-disubstituted oxepene skeleton was stereoselectively constructed via cyclization of the hydroxy epoxide promoted by the (Bu3Sn)2O/Zn(OTf)2 system. The proposed configurations of 6R and 13R were confirmed through this synthetic study.