333788-78-6Relevant articles and documents
The first total synthesis of (+)-rogioloxepane A
Matsumura, Ryuji,Suzuki, Toshio,Hagiwara, Hisahiro,Hoshi, Takashi,Ando, Masayoshi
, p. 1543 - 1546 (2007/10/03)
The first total synthesis of (+)-rogioloxepane A is described. The α,ω-trans-disubstituted oxepene skeleton was stereoselectively constructed via cyclization of the hydroxy epoxide promoted by the (Bu3Sn)2O/Zn(OTf)2 system. The proposed configurations of 6R and 13R were confirmed through this synthetic study.