333795-10-1 Usage
Molecular weight
324.4
Structure
A piperidine ring with a carboxyl group, a phenyl ring attached to the piperidine ring, and a Boc protective group on the amino group.
Appearance
White crystalline solid
Solubility
Soluble in organic solvents such as methanol, ethanol, and acetonitrile
Use
Commonly used in medicinal chemistry and peptide synthesis as a building block for the synthesis of peptide-based pharmaceuticals and bioactive compounds.
Functional groups
Carboxyl, amino, and Boc protective group
Reactivity
The Boc protective group can be removed under acidic conditions to reveal the free amino group, allowing for further reactions and modifications.
Stability
Stable under normal conditions, but sensitive to strong acids and bases.
Potential
Has shown potential as a chemical building block for the development of novel drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 333795-10-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,3,7,9 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 333795-10:
(8*3)+(7*3)+(6*3)+(5*7)+(4*9)+(3*5)+(2*1)+(1*0)=151
151 % 10 = 1
So 333795-10-1 is a valid CAS Registry Number.
333795-10-1Relevant articles and documents
Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent anti-HIV-1 activity
Imamura, Shinichi,Ichikawa, Takashi,Nishikawa, Youichi,Kanzaki, Naoyuki,Takashima, Katsunori,Niwa, Shinichi,Iizawa, Yuji,Baba, Masanori,Sugihara, Yoshihiro
, p. 2784 - 2793 (2007/10/03)
We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety
