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Phenol, 4-nitro-2-(2-pyridinyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

33400-82-7

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33400-82-7 Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 93, p. 3074, 1971 DOI: 10.1021/ja00741a059

Check Digit Verification of cas no

The CAS Registry Mumber 33400-82-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,4,0 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 33400-82:
(7*3)+(6*3)+(5*4)+(4*0)+(3*0)+(2*8)+(1*2)=77
77 % 10 = 7
So 33400-82-7 is a valid CAS Registry Number.

33400-82-7Relevant academic research and scientific papers

Palladium-catalyzed aryl C(sp2)-H bond hydroxylation of 2-arylpyridine using TBHP as oxidant

Dong, Jiawei,Liu, Ping,Sun, Peipei

, p. 2925 - 2929 (2015/03/18)

An efficient synthesis of phenols via Pd-catalyzed, pyridyl-directed homogeneous hydroxylation of the aryl C-H bond was developed, in which tert-butyl hydroperoxide was used as the sole oxidant. The method had a broad group tolerance and was available for

A facile synthetic route for antineoplastic drug GDC-0449

Cao, Meng,Hu, Hua-You,Zhao, Hu-Cheng,Zhang, Xi-Quan,Gu, Hong-Mei,Yang, Ling,Cai, Jin,Wang, Peng,Hu, Bing,Ji, Min

, p. 1408 - 1414 (2014/07/21)

In the current study a facile synthetic route for preparing antineoplastic drug GDC-0449 is investigated. Starting with pyridine-1-oxide and 1-iodo-3-nitrobenzene, the intermediate product 2-(2-chloro-5-nitrophenyl) pyridine was prepared by cross-coupling

Squaric Acid Derivatives as Protein Kinase Inhibitors

-

Page/Page column 20, (2009/01/24)

Compounds of the formula I, in which R, X, R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of CHK1 CHK2 and SGK kinases and can be employed, inter alia, for the treatment

TAUTOMERS OF AZINE DERIVATIVES. 21. TAUTOMERISM IN 2-(2-HYDROXYARYL)AZINES

Stekhova, S. A.,Lapachev, V. V.,Mamaev, V. P.

, p. 65 - 70 (2007/10/02)

Tautomerism in 2-(2-hydroxyaryl)azines has been studied using 17O NMR and UV spectroscopy.Consideration has been given to the influence of solvent and structural factors which facilitate the establishment of a tautomeric equilibrium in these compounds.

Base-Catalyzed Rearrangement of N-(Aryloxy)pyridinium Salts. Effect of a 3-Substituent in the Pyridine Ring upon Orientation. Synthesis of Novel Tricyclic Rings

Abramovitch, Rudolph A.,Inbasekaran, Muthiah N.,Kato, Shozo,Radzikowska, Teresa A.,Tomasik, Piotr

, p. 690 - 695 (2007/10/02)

The orientation in the base-catalyzed rearrangement of 3-substituted N-(aryloxy)pyridinium tetrafluoroborates (5) to 2- or 6-(2-hydroxyaryl)pyridines has been studied.A 3-methyl group directs exclusively to the 6-position while inductively electron-withdrawing substituents (Cl, Br, I, OMe, CO2Me, COMe) direct mainly, if not exclusively, to C-2.The phenols derived from 3-CO2Me derivates cyclize spontaneously to the substituted pyridocoumarins (8) in useful yields, and that from the 3-COMe compound gives 10-hydroxy-10-methyl-6-nitropyridobenzopyran (9).The 3-halo-2-(2-hydroxyaryl)pyridines cyclize to benzofuropyridines(10,15) on heating with potassium hydroxide and copper powder.Authentic benzofuropyridine (12) is obtained by the Pschorr ring closure of the diazonium salt of 3-(o-aminophenoxy)pyridine (14).The substituent effects are explained mainly on the basis of the inductive effect of the substituent: steric effects play a slight role.A minor side reaction is thought to involve the intermediacy of free radicals.

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