33421-36-2Relevant articles and documents
SYNTHESIS OF 2-(2'-HYDROXYPHENYL)PYRIDINE-N-OXIDE AND ITS THERMAL DECOMPOSITION AS A MODEL REACTION OF ORELLANINE DEOXIDATION
Antkowiak, Wieslaw Z.,Gessner, Wieslaw P.
, p. 4045 - 4048 (1984)
2-Methoxyphenylmagnesium bromide was reacted with 2-nitropyridine-N-oxide and demethylated to give 2-(2'-hydroxyphenyl)pyridine-N-oxide (II) which was found to undergo a thermal deoxidation to the free base (VI); the process is interpreted as a oxygen shift followed by decomposition of the hydroperoxide intermediate.
Amination of the ortho C-H bonds by the Cu(OAc)2-mediated reaction of 2-phenylpyridines with anilines
Uemura, Takeshi,Imoto, Shinya,Chatani, Naoto
, p. 842 - 843 (2006)
The reaction of 2-phenylpyridines with anilines in the presence of Cu(OAc)2 as a promoter results in selective mono-amination of the ortho C-H bonds in 2-phenylpyridines to give amine derivatives in high yields per the conversion. This is the r
Synthesis and characterization of mixed ligand cyclopalladates with 2-phenylpyridine and substituted phenanthrolines: Investigation into the hydroxylation reaction of 2-phenylpyridine
Garypidou, Antonia,Ypsilantis, Konstantinos,Tsolis, Theodoros,Kourtellaris, Andreas,Plakatouras, John C.,Garoufis, Achilleas
, (2021)
Mixed ligand cyclopalladated complexes with 2-phenylpyridine (ppy) and 2,9-dimethyl-1,10-phenanthroline (ncp), 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (bcp), 4,7-diphenyl-1,10-phenanthroline (bphen) were synthesized and characterized. The crystal st
Exploring oxidation of half-sandwich rhodium complexes: Oxygen atom insertion into the rhodium-carbon bond of κ2-coordinated 2-phenylpyridine
Turlington, Christopher R.,Morris, James,White, Peter S.,Brennessel, William W.,Jones, William D.,Brookhart, Maurice,Templeton, Joseph L.
, p. 4442 - 4448 (2014)
The reactions of oxygen atom transfer reagents with Rh(Cp) complexes, each with a bidentate ligand and an accessible coordination site, are described (Cp = η5-pentamethylcyclopentadienyl). When [Rh(Cp)(phpy)(NCArF)][B(ArF)
Nickel/zinc-mediated alkyl carbon-oxygen bond cleavage of alkyl aryl ethers
Maeyama, Katsuya,Kobayashi, Masato,Yonezawa, Noriyuki
, p. 869 - 875 (2001)
Alkyl carbon-oxygen bonds of alkyl aryl ethers bearing suitable coordination sites were efficiently cleaved by treatment with nickel(II) chloride and zinc in p-xylene under neutral conditions.
Synthesis and Characterization of Oxazaborinin Phosphonate for Blue OLED Emitter Applications
K?hling, Jonas,Kozel, Volodymyr,Jovanov, Vladislav,Pajkert, Romana,Tverdomed, Sergey N.,Gridenco, Oleg,Fugel, Malte,Grabowsky, Simon,R?schenthaler, Gerd-Volker,Wagner, Veit
, p. 665 - 671 (2019)
A blue-light emitting material based on a boron complex containing heteroaromatic phosphonate ligand is synthesized and characterized. The Phospho-Fries rearrangement is used in the synthesis route of the ligand as a convenient method of introducing phosp
Synthesis of 2-(2-Hydroxyaryl)-4H-benzo[e][1,3]oxazin-4-ones by Palladium-Catalyzed C(sp2)?H Hydroxylation via Electro-chemical Oxidation
Wu, Hongfeng,An, Qi,He, Chaoyin,Fan, Xiaodong,Guo, Weihao,Zuo, Minghui,Xu, Chunzhao,Guo, Rui,Chu, Wenyi,Sun, Zhizhong
supporting information, p. 2459 - 2465 (2020/04/29)
An electrochemical direct ortho-hydroxylation of 2-aryl-4H-benzo[e][1,3]oxazin-4-ones was developed with Pd(OAc)2 as catalyst, oxazine ring as a directing group and Oxone as the hydroxylation reagent. A series of hydroxylation products were obtained under mild conditions, and the yields were from medium to good. This method is characterized by good functional group tolerance and a wide range of substrates. More importantly, use anodic oxidation to avoid the use of potentially toxic and polluting oxidants. A gram-scale direct electrochemical hydroxylation of 2-phenyl-4H-benzo[e][1,3]oxazin-4-one was performed, and the hydroxylation product was applied to synthesize the drug deferasirox. In addition, the single crystal of 2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one was obtained and determined by X-ray diffraction. Finally, the reaction mechanism was proposed and verified by cyclic voltammetry (CV). This protocol also provides an alternative electrochemical hydroxylation methodology for the functionalization of molecules. (Figure presented.).
