33402-63-0Relevant academic research and scientific papers
I2/TBHP Mediated C-N and C-H Bond Cleavage of Tertiary Amines toward Selective Synthesis of Sulfonamides and β-Arylsulfonyl Enamines: The Solvent Effect on Reaction
Lai, Junyi,Chang, Liming,Yuan, Gaoqing
, p. 3194 - 3197 (2016)
A novel method toward synthesis of sulfonamides and β-arylsulfonyl enamines has been developed via I2/TBHP mediated C-N and C-H bond cleavage of tertiary amines, which features highly selective formation of two different target products depending on the reaction solvent. The experimental results reveal that H2O as the solvent could effectively achieve the C-N bond cleavage to produce sulfonamides due to H2O participating in the reaction process where H2O plays a dual role. Differing from H2O, organic solvents (such as dimethyl sulfoxide) could promote the C-H bond cleavage of tertiary amines to yield β-arylsulfonyl enamines.
Method for synthesizing benzsulfamide compound from benzene sulfonyl chloride compound and triethylamine without metal catalysis
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Paragraph 0030-0031, (2019/02/04)
The invention relates to a method for synthesizing a benzsulfamide compound from a benzene sulfonyl chloride compound and triethylamine without metal catalysis. The benzsulfamide compound is generatedby adopting the benzene sulfonyl chloride compound and
Synthesis of sulfonamides: Via copper-catalyzed oxidative C-N bond cleavage of tertiary amines
Ji, Jing,Liu, Zhengyi,Liu, Ping,Sun, Peipei
, p. 7018 - 7023 (2016/07/30)
A copper-catalyzed coupling reaction of sulfonyl chlorides with tertiary amines via the oxidative C-N bond cleavage of tertiary amines was developed. Sulfonamides were synthesized using this strategy in moderate to good yields. The reaction was applicable to various tertiary amines, as well as sulfonyl chlorides.
Method for Preparing Halogenated Amines
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Page/Page column 17-18, (2008/12/07)
This invention relates to methods for preparing halogenated amines.
Facile one-pot synthesis of aromatic and heteroaromatic sulfonamides
Pandya, Rina,Murashima, Takashi,Tedeschi, Livio,Barrett, Anthony G. M.
, p. 8274 - 8276 (2007/10/03)
A series of arene and heteroarene sulfonamides were prepared in one vessel from aryl and heteroaryl bromides via conversion into the corresponding Grignard reagents using either magnesium or isopropylmagnesium chloride and subsequent reaction with sulfur dioxide, sulfuryl chloride, and an amine.
