334025-50-2Relevant academic research and scientific papers
NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES
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, (2008/06/13)
This invention relates to a diarylamide derivative represented by formula (1) or a salt thereof and a pharmaceutical composition comprising, as an active ingredient, the compound: wherein, ???A and B denote an aromatic ring such as a benzene ring; COY and NHCOX are adjacent to each other and these substituents are linked to carbon in the aromatic ring A; X denotes alkylene, alkyleneoxy, or a single bond; Y denotes an alkyl, alkoxy, hydroxyl, or substituted or unsubstituted amino group; R1 denotes hydrogen, halogen, hydroxyl, alkyl or the like, provided that, when A denotes a benzene ring, R1 does not denote hydrogen; R2 denotes hydrogen, halogen, hydroxyl, alkyl or the like; R3 and R4 denote a substituted or unsubstituted imino group, an oxygen atom, or a single bond; R5 denotes alkyl, substituted or unsubstituted phenyl or the like; and Z denotes oxygen or sulfur.
