33452-25-4

Basic information

• Product Name: Methanone, (1-methyl-1H-tetrazol-5-yl)phenyl-
• CAS NO: 33452-25-4
• Molecular Formula: C9H8N4O
• Molecular Weight: 188.189
• Mol File: 33452-25-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Methanone, (1-methyl-1H-tetrazol-5-yl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (1-methyl-1H-tetrazol-5-yl)phenyl-(33452-25-4)
• EPA Substance Registry System: Methanone, (1-methyl-1H-tetrazol-5-yl)phenyl-(33452-25-4)

Safety Data

• Hazardous Substances Data: 33452-25-4(Hazardous Substances Data)

Upstream product

• 1202945-76-3 but-3-yn-1-yl (6-(((((1-methyl-1H-tetrazol-5-yl)(phenyl)methylene)amino)oxy)methyl)pyridin-2-yl)carbamate 
• 613-90-1 benzoyl cyanide 
• 624-90-8 methyl azide 
• 83490-71-5 N?methyl?2?oxo?2?phenylacetamide 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 1449795-25-8 sodium {[(1-methyl-1H-tetrazol-5-yl)(phenyl)ethylene]amino}oxidanide 
• 98-86-2 acetophenone 

Downstream Products

• 1083086-53-6 (Z)?(1?methyl?1H?tetrazol?5?yl)(phenyl)methanone oxime 
• 14506-41-3 phenyl(1H-tetrazol-5-yl)methanone 

Relevant articles and documents

Generation of hazardous methyl azide and its application to synthesis of a key-intermediate of picarbutrazox, a new potent pesticide in flow

Generation and reactions of methyl azide (MeN3) were successfully performed by using a flow reactor system, demonstrating that the flow method serves as a safe method for handling hazardous explosive methyl azide. The reaction of NaN3 and Me2SO4 in a flow reactor gave a MeN3 solution, which was used for Huisgen reaction with benzoyl cyanide in a flow reactor after minimal washing. The resulting 1-methyl-5-benzoyltetrazole serves as a key intermediate of picarbutrazox (IX), a new potent pesticide.

Novel oxime derivative as well as preparation method and application thereof

The invention relates to a novel oxime derivative and a preparation method and application thereof, the novel oxime derivative has a structure as shown in formula (I), Q is optionally substituted phenyl, T is C1-6 alkyl substituted tetrazolyl, and A is th

Design, synthesis, and biological evaluation of phenyloxadiazole derivatives as potential antifungal agents against phytopathogenic fungi

Abstract: A novel series of picarbutrazox-inspired oxadiazole hybrids was synthesized and the derivatives’ biological activity against phytopathogenic fungi was investigated. The molecules were designed by retaining the active fragment of tetrazolyl phenyloxime ether of lead compound picarbutrazox, while introducing the potentially active oxadiazole-derived fragment. Bioassay results revealed that some of the title compounds showed potent in vivo antifungal activities to control cucumber downy mildew. Therefore, this novel oxadiazole phenyloxadiazole derivative can be used as a potential antifungal agent to control cucumber downy mildew and other phytopathogenic fungi for crop protection. Graphic abstract: [Figure not available: see fulltext.].