33468-36-9 Usage
General Description
(S)-2-AMINO-3-(7-METHYL-1H-INDOL-3-YL)-PROPIONIC ACID, also known as Tryptophan, is a crucial alpha-amino acid that plays a significant role in human biology. It is used in the biosynthesis of proteins, and it contains an indole functional group, typically attached to an ethyl side chain. Being one of the essential amino acids, it needs to be obtained from one's diet because the human body cannot produce it. Some sources of Tryptophan are eggs, cheese, tofu, salmon, and turkey. Moreover, it plays a critical role in the production of serotonin —a neurotransmitter that sends signals between nerve cells and is thought to promote healthy sleep and regulate mood. (S)-2-AMINO-3-(7-METHYL-1H-INDOL-3-YL)-PROPIONIC ACID ordinarily contains a carboxylic acid group (-COOH), an amino group (-NH2), and a side chain denoted as "R," making it a derivative of the main carbon structure.
Check Digit Verification of cas no
The CAS Registry Mumber 33468-36-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,4,6 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 33468-36:
(7*3)+(6*3)+(5*4)+(4*6)+(3*8)+(2*3)+(1*6)=119
119 % 10 = 9
So 33468-36-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O2/c1-7-3-2-4-9-8(6-14-11(7)9)5-10(13)12(15)16/h2-4,6,10,14H,5,13H2,1H3,(H,15,16)
33468-36-9Relevant articles and documents
Preparation method of non-natural L - tryptophan derivative
-
, (2021/11/21)
The invention discloses a preparation method of a non-natural L - tryptophan derivative, which is sequentially subjected to formylation by adopting a cheap and easily available substituted indole compound as a raw material. Cyclization, ring opening, asym
Synthesis of tripeptides containing d-Trp substituted at the indole ring, assessment of opioid receptor binding and in vivo central antinociception
De Marco, Rossella,Bedini, Andrea,Spampinato, Santi,Gentilucci, Luca
, p. 6861 - 6866 (2014/10/15)
The noncationizable tripeptide Ac-d-Trp-Phe-GlyNH2 was recently proposed as a novel minimal recognition motif for μ-opioid receptor. The introduction of different substituents (methyl, halogens, nitro, etc.) at the indole of d-Trp significantly influenced receptor affinities and resulted in serum stability and in a measurable effect on central antinociception in mice after ip administration.