334705-96-3Relevant articles and documents
Synthesis of isopropenylcyclopropanes - Revision of the relative configuration of cyclopropyl ketones obtained by 1,3-elimination of γ-epoxy ketones
Cossy, Janine,Blanchard, Nicolas,Meyer, Christophe
, p. 339 - 348 (2001)
Efficient stereoselective routes towards isopropenylcyclopropanes have been devised. Secondary cis-isopropenylcyclopropylcarbinols have been obtained either by regio- and stereoselective hydroxy-directed cyclopropanation of the corresponding dienols or from bicyclic cyclopropyl lactones derived from intramolecular cyclopropanation of allylic diazoacetates. Contrary to previous reports, base-induced 1,3-elimination of γ-epoxy ketones has been shown to afford trans-2-(hydroxymethyl)cyclopropyl ketones, and the reactivity of these compounds has been reinvestigated.
Total synthesis of zincophorin and its methyl ester
Defosseux, Magali,Blanchard, Nicolas,Meyer, Christophe,Cossy, Janine
, p. 4626 - 4647 (2007/10/03)
A total synthesis of the naturally occurring ionophore zincophorin has been realized. The route features an intramolecular oxymercuration of a cyclopropanemethanol and a Carroll-Claisen rearrangement for the respective elaboration of the C1-C12 and C13-C25 subunits, which have been assembled by using a highly diastereoselective titanium-mediated aldol condensation.