460997-49-3Relevant articles and documents
Total synthesis of zincophorin and its methyl ester
Defosseux, Magali,Blanchard, Nicolas,Meyer, Christophe,Cossy, Janine
, p. 4626 - 4647 (2007/10/03)
A total synthesis of the naturally occurring ionophore zincophorin has been realized. The route features an intramolecular oxymercuration of a cyclopropanemethanol and a Carroll-Claisen rearrangement for the respective elaboration of the C1-C12 and C13-C25 subunits, which have been assembled by using a highly diastereoselective titanium-mediated aldol condensation.
A synthetic approach towards the C1-C9 subunit of zincophorin
Cossy, Janine,Blanchard, Nicolas,Defosseux, Magali,Meyer, Christophe
, p. 2144 - 2146 (2007/10/03)
Antibiotics made from cyclopropylmethanols: The C1-C9 subunit (2) of zincophorin (1) has been synthesized by using three key steps: a hydroboration of an enantiomerically enriched isopropenylcyclopropane, an aldol reaction, and an intramolecular oxymercur